Phavichitr Nopaorn, Koosiriwichian Kalayanee, Tantibhaedhyangkul Ruangvith
Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand.
J Med Assoc Thai. 2012 May;95 Suppl 5:S42-7.
Dyspepsia is a common form of chronic abdominal pain in children and adolescents. Although it is usually functional or non-organic in origin, it disturbs daily activities, school attendance and the child's wellbeing. The authors evaluated prevalence and factors associated with dyspepsia among schoolchildren by comparing life-style of dyspeptic children with their asymptomatic peers.
Total 1181 schoolchildren (mean age 14.7 +/- 1.8 years) were recruited from three schools in Bangkok. Data on dyspeptic symptoms were collected by using a questionnaire based on Rome III classification system. Potential precipitating factors for dyspepsia and life-style related to dyspepsia were also explored in the questionnaire.
Dyspepsia was reported in 24.0% of the subjects. Prevalence was significantly higher in girls than in boys (27.0% vs. 20.0% p = 0.006). There was no difference between the comparison groups in terms of school test scores, past medical illness, parental marital status, parental income, number of siblings,frequency of stool and spicy food, carbonated beverage or dairy product consumption. The dyspepsia group had higher percentage of family history of peptic ulcer (odds ratio [OR] = 2.5 [95% CI = 1.7 to 3.7]), history of taking medicine (OR 1.7 [1 .0 to 2.9]), alcohol consumption (OR 2.4 [1.0 to 5.7]), severe stress (OR = 3.4 [1.2 to 9.9]) and extreme stress (OR = 3.9 [1.3 to 12.0]).
Prevalence of self-reported dyspepsia among schoolchildren in this survey was similar to those previously reported; with family history of peptic ulcer, history of taking medicine, alcohol consumption, stresses in life as potential risk factors.
消化不良是儿童和青少年慢性腹痛的常见形式。尽管其病因通常为功能性或非器质性，但会干扰日常活动、上学以及儿童的健康状况。作者通过比较消化不良儿童与其无症状同伴的生活方式，评估了学童中消化不良的患病率及相关因素。
从曼谷的三所学校招募了1181名学童（平均年龄14.7±1.8岁）。使用基于罗马III分类系统的问卷收集消化不良症状的数据。问卷中还探讨了消化不良的潜在诱发因素以及与消化不良相关的生活方式。
24.0%的受试者报告有消化不良。女孩的患病率显著高于男孩（27.0%对20.0%，p = 0.006）。在学校考试成绩、既往病史、父母婚姻状况、父母收入、兄弟姐妹数量、大便频率以及辛辣食物、碳酸饮料或乳制品消费频率方面，比较组之间没有差异。消化不良组有消化性溃疡家族史（优势比[OR]=2.5[95%置信区间=1.7至3.7]）、服药史（OR 1.7[1.0至2.9]）、饮酒（OR 2.4[1.0至5.7]）、严重压力（OR = 3.4[1.2至9.9]）和极度压力（OR = 3.9[1.3至12.0]）的比例更高。
本次调查中学童自我报告的消化不良患病率与先前报告的相似；消化性溃疡家族史、服药史、饮酒、生活压力为潜在风险因素。
