Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven 3720 BA, the Netherlands.
BMC Public Health. 2012 Aug 30;12:715. doi: 10.1186/1471-2458-12-715.
Multimorbidity is increasingly recognized as a major public health challenge of modern societies. However, knowledge about the size of the population suffering from multimorbidity and the type of multimorbidity is scarce. The objective of this study was to present an overview of the prevalence of multimorbidity and comorbidity of chronic diseases in the Dutch population and to explore disease clustering and common comorbidities.
We used 7 years data (2002-2008) of a large Dutch representative network of general practices (212,902 patients). Multimorbidity was defined as having two or more out of 29 chronic diseases. The prevalence of multimorbidity was calculated for the total population and by sex and age group. For 10 prevalent diseases among patients of 55 years and older (N = 52,014) logistic regressions analyses were used to study disease clustering and descriptive analyses to explore common comorbid diseases.
Multimorbidity of chronic diseases was found among 13% of the Dutch population and in 37% of those older than 55 years. Among patients over 55 years with a specific chronic disease more than two-thirds also had one or more other chronic diseases. Most disease pairs occurred more frequently than would be expected if diseases had been independent. Comorbidity was not limited to specific combinations of diseases; about 70% of those with a disease had one or more extra chronic diseases recorded which were not included in the top five of most common diseases.
Multimorbidity is common at all ages though increasing with age, with over two-thirds of those with chronic diseases and aged 55 years and older being recorded with multimorbidity. Comorbidity encompassed many different combinations of chronic diseases. Given the ageing population, multimorbidity and its consequences should be taken into account in the organization of care in order to avoid fragmented care, in medical research and healthcare policy.
多重疾病日益被视为现代社会的主要公共卫生挑战。然而,有关患有多重疾病的人群规模和多重疾病类型的知识却很少。本研究的目的是概述荷兰人群中多重疾病和慢性疾病合并症的流行情况,并探讨疾病聚类和常见合并症。
我们使用了一个大型荷兰普通实践网络(212,902 名患者)的 7 年数据(2002-2008 年)。将两种或两种以上的 29 种慢性疾病定义为多重疾病。计算了总人群以及按性别和年龄组划分的多重疾病的患病率。对于 55 岁及以上患者中的 10 种常见疾病(N=52,014),使用逻辑回归分析研究疾病聚类,使用描述性分析探索常见合并症。
13%的荷兰人口患有慢性多重疾病,37%的55 岁以上人口患有慢性多重疾病。在 55 岁以上患有特定慢性疾病的患者中,超过三分之二的患者还患有一种或多种其他慢性疾病。大多数疾病对出现的频率高于如果疾病是独立的情况下所预期的频率。合并症不仅限于特定的疾病组合;约 70%的患有疾病的患者记录了一种或多种额外的慢性疾病,这些疾病未包含在最常见疾病的前五名中。
多重疾病在所有年龄段都很常见,尽管随着年龄的增长而增加,患有慢性疾病和 55 岁及以上的患者中,超过三分之二的患者患有多重疾病。合并症包括许多不同的慢性疾病组合。鉴于人口老龄化,在组织医疗保健时应考虑到多重疾病及其后果,以避免医疗碎片化,并应在医学研究和医疗保健政策中考虑到这些问题。