Department of Infectious Diseases, University of Washington, Seattle, WA 98105, USA.
Pediatr Infect Dis J. 2012 Dec;31(12):1307-9. doi: 10.1097/INF.0b013e3182700e34.
Wound botulism arising from skin and soft tissue infection is rare in children, most cases being reported in adult intravenous drug users. Cranial nerve palsies are the primary presenting sign, followed by descending neuromuscular weakness. Diagnosis relies on isolation of either toxigenic Clostridium botulinum species or toxin from wound or blood samples. We present an unusual case of wound botulism in a pediatric patient with the intent to inform the reader and improve the time to diagnosis in such cases.
由皮肤和软组织感染引起的创伤性肉毒中毒在儿童中较为罕见，大多数病例见于成年静脉吸毒者。颅神经麻痹是主要的首发症状，随后出现进行性神经肌肉无力。诊断依赖于从伤口或血液样本中分离出产毒梭菌或毒素。我们报告了一例儿科创伤性肉毒中毒的罕见病例，旨在为读者提供信息，并提高此类病例的诊断时间。
