Burningham M D, Walter F G, Mechem C, Haber J, Ekins B R
Department of Emergency Medicine, Valley Medical Center, University of California, San Francisco School of Medicine.
Ann Emerg Med. 1994 Dec;24(6):1184-7. doi: 10.1016/s0196-0644(94)70253-5.
Wound botulism is a rare infectious and toxicologic complication of trauma and i.v. drug abuse. Only 39 cases have been reported in detail in the English literature. This case report describes a patient with wound botulism who presented to four medical facilities before receiving definitive diagnosis and treatment. Although his history and physical examination were consistent with wound botulism, diagnosis and therapy were delayed because this rare disease was not considered initially in the differential diagnosis. Wound botulism should be considered in trauma patients and i.v. drug abusers who present with cranial nerve palsies and descending paresis.
创伤性肉毒中毒是创伤和静脉药物滥用罕见的感染性和毒理学并发症。英文文献中仅详细报道了39例。本病例报告描述了一名创伤性肉毒中毒患者,该患者在接受明确诊断和治疗前曾就诊于四家医疗机构。尽管其病史和体格检查与创伤性肉毒中毒相符,但诊断和治疗仍被延误,因为这种罕见疾病在最初的鉴别诊断中未被考虑。对于出现颅神经麻痹和下行性麻痹的创伤患者和静脉药物滥用者,应考虑创伤性肉毒中毒。