在腮腺炎流行期间患有明显睾丸炎的部分人群的精液分析图

Spermiogram part of population with the manifest orchitis during an ongoing epidemic of mumps.

作者信息

Gazibera Belma, Gojak Refet, Drnda Alija, Osmic Akif, Mostarac Nermin, Jusufi-Huric Ilhama, Muratovic Planinka

机构信息

Clinic for the Infectious Diseases, Clinical center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

出版信息

Med Arch. 2012;66(3 Suppl 1):27-9. doi: 10.5455/medarh.2012.66.s27-s29.

DOI:10.5455/medarh.2012.66.s27-s29

PMID:22937687

Abstract

INTRODUCTION

Incidence mumps infection has declined since the introduction of the inevitable MRP vaccination during the stage of childhood. In Bosnia and Herzegovina (BIH), from a period of February 2011 until today, there is an evident inclination of the recorded cases of the mumps infection. Orchitis usually occurs in between 3 to 10 days after the parotitis and is found with the post-puberty population.

AIM

The aim of the study is to confirm the changes that occur during an early stage of the spermiogram and hormonal status, and after treated mumps orchitis, the patients treated in the Clinic for the Infectious Diseases.

PATIENTS AND METHODS

Retrospectively, the analysis of 54 historical diseases was undertaken. During the research stage, the patients after being discharged have made an inquiry to our clinical consultancy units with final results of the spermiogram and hormone-FSH, LH and testosteron. The data analysis was processed with the SPSS program for Windows.

RESULTS

the average length of the hospitalization period was in between 8 (medium) days, and average age M (mean) = 21,9 +/- 5,4 years. The speriogram of the treated patients was undertaken one month after the acute phase of the disease and has shown the following results: azoospermia with 14 patients (25,9%), oligospermia with 30 patients (55,6%) and normospermia with 10 patients (18,5%). During the hormonal status with 11 patients (20,4%), the results have shown the inclination of the value in FSH hormons, with 11 patients (20,4%), have shown the lesser value of the testosterons.

CONCLUSION

The current study suggests that post-orhitis atrofia is expected within a period of 2-3 months after the infection, and thus, the monitoring on the patients' treatment would continue. The male infertility as a result of mumps ocrhitis is controversial and continues to be the thematic issue as well as the effect of orchitis on testicular endocrine function. Key words: epidemic, mumps

摘要

引言

自儿童期引入腮腺炎、风疹、麻疹联合疫苗（MMR）后，腮腺炎感染的发病率有所下降。在波斯尼亚和黑塞哥维那（波黑），从2011年2月至今，腮腺炎感染病例有明显上升趋势。睾丸炎通常在腮腺炎发病后3至10天出现，且多见于青春期后的人群。

目的

本研究旨在确认在精液分析和激素状态早期阶段以及在传染病诊所接受治疗的腮腺炎睾丸炎患者治疗后所发生的变化。

患者与方法

回顾性分析54例既往病例。在研究阶段，出院后的患者向我们的临床咨询单位询问了精液分析以及激素促卵泡激素（FSH）、促黄体生成素（LH）和睾酮的最终结果。数据分析采用适用于Windows的SPSS程序进行处理。

结果

平均住院时间为8天（中位数），平均年龄M（均值）=21.9±5.4岁。治疗患者的精液分析在疾病急性期后1个月进行，结果如下：无精子症14例（25.9%），少精子症30例（55.6%），正常精子症10例（18.5%）。在激素状态方面，11例患者（20.4%）促卵泡激素值有上升趋势，11例患者（20.4%）睾酮值较低。