累积风险评估 (CRA)：改变我们评估健康风险的方式。
Cumulative Risk Assessment (CRA): transforming the way we assess health risks.
机构信息
E Risk Sciences, LLP, Boulder, Colorado, USA.
出版信息
Environ Sci Technol. 2012 Oct 16;46(20):10868-74. doi: 10.1021/es3025353. Epub 2012 Sep 11.
Abstract
Human health risk assessments continue to evolve and now focus on the need for cumulative risk assessment (CRA). CRA involves assessing the combined risk from coexposure to multiple chemical and nonchemical stressors for varying health effects. CRAs are broader in scope than traditional chemical risk assessments because they allow for a more comprehensive evaluation of the interaction between different stressors and their combined impact on human health. Future directions of CRA include greater emphasis on local-level community-based assessments; integrating environmental, occupational, community, and individual risk factors; and identifying and implementing common frameworks and risk metrics for incorporating multiple stressors.
摘要
人类健康风险评估不断发展，现在侧重于需要进行累积风险评估 (CRA)。CRA 涉及评估多种化学和非化学应激因素共同暴露对不同健康影响的综合风险。CRA 的范围比传统的化学风险评估更广泛，因为它们允许更全面地评估不同应激因素之间的相互作用及其对人类健康的综合影响。CRA 的未来发展方向包括更加重视基于社区的地方层面评估；整合环境、职业、社区和个体风险因素；以及确定和实施共同的框架和风险指标，以纳入多种应激因素。
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