Takagi S, Chow L C, Schreiber C T
American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Md.
Caries Res. 1990;24(1):18-22. doi: 10.1159/000261231.
Application of monocalcium phosphate monohydrate (MCPM) gel, which produces small amounts of dicalcium phosphate dihydrate in enamel, was previously shown to increase the enamel reactivity with fluoride (F). This study was conducted to determine whether the MCPM gel treatment is also effective in enhancing F uptake by root surfaces of human teeth. The results show that samples receiving daily treatments with MCPM gel for 10 min followed by immersion in a 1-ppm F solution for 5 days acquired a significantly greater amount of F compared to the controls which had the same exposure to the F solution. Because the F solution was undersaturated with respect to calcium fluoride (CaF2), the F incorporated into the root is apparently apatitic and not CaF2. This experimental treatment should be feasible in the clinical situation since only a short treatment time was required and delivery of the MCPM gel to specific sites was relatively easy.
先前的研究表明，应用一水磷酸二氢钙（MCPM）凝胶（其在牙釉质中会产生少量二水磷酸二钙）可提高牙釉质与氟（F）的反应活性。本研究旨在确定MCPM凝胶处理对增强人牙根表面氟摄取是否也有效。结果显示，与同样暴露于氟溶液的对照组相比，每天用MCPM凝胶处理10分钟，然后浸入1 ppm氟溶液中5天的样本摄取的氟量显著更多。由于氟溶液相对于氟化钙（CaF2）不饱和，因此结合到牙根中的氟显然是磷灰石形式的，而非CaF2。这种实验性处理在临床情况下应该是可行的，因为所需的处理时间较短，并且将MCPM凝胶递送至特定部位相对容易。
