Tower S S, Pratt W B
Department of Orthopedic Surgery, Alaska Native Medical Center, Anchorage.
Clin Orthop Relat Res. 1990 Jan(250):171-5.
Roentgenographic and anthropologic studies have shown a high incidence of spondylolysis in Eskimo populations. It is uncertain whether this is related to a genetic predisposition or to environmental factors. This study of recent roentgenograms and demographic characteristics of patients of the authors' institution notes a lower incidence in Eskimo populations than prior skeletal and roentgenographic studies. An attempt is made to quantitate the contributions of environmental factors and genetic predisposition. A higher incidence was found in full-blooded Eskimos than in part-blooded Eskimos. Rural-dwelling Eskimos had a higher incidence than urban-dwelling Eskimos. Eskimo subpopulations had a greater incidence than Athabascan Indians. Eskimos with spondylolysis were significantly more likely to have an associated spondylolisthesis than Athabascans with spondylolysis. Symptoms in the Eskimo population related to spondylolysis and associated spondylolisthesis rarely warrant surgical intervention.
X线摄影和人类学研究表明，爱斯基摩人群中椎弓根峡部裂的发病率很高。目前尚不确定这是与遗传易感性还是环境因素有关。这项对作者所在机构患者近期X线片和人口统计学特征的研究指出，爱斯基摩人群中的发病率低于先前的骨骼和X线摄影研究。本文试图对环境因素和遗传易感性的作用进行量化。研究发现，纯血统爱斯基摩人的发病率高于混血爱斯基摩人。居住在农村的爱斯基摩人的发病率高于居住在城市的爱斯基摩人。爱斯基摩亚人群的发病率高于阿萨巴斯卡印第安人。与患有椎弓根峡部裂的阿萨巴斯卡人相比，患有椎弓根峡部裂的爱斯基摩人更有可能伴有椎体滑脱。爱斯基摩人群中与椎弓根峡部裂及相关椎体滑脱相关的症状很少需要手术干预。
