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腹主导鼻:进食状态依赖的外周化学感觉反应调制。

The belly rules the nose: feeding state-dependent modulation of peripheral chemosensory responses.

机构信息

Department of Biology and the National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, United States.

出版信息

Curr Opin Neurobiol. 2013 Feb;23(1):68-75. doi: 10.1016/j.conb.2012.08.001. Epub 2012 Aug 29.

Abstract

Feeding history and the presence of food dramatically alter chemosensory behaviors. Recent results indicate that internal nutritional state can gate peripheral gustatory and olfactory sensory responses to affect behavior. Focusing primarily on recent work in C. elegans and Drosophila, I describe the neuromodulatory mechanisms that translate feeding state information into changes in chemosensory neuron response properties and behavioral output.

摘要

进食历史和食物的存在显著改变了化学感觉行为。最近的研究结果表明,内部营养状态可以调节外周味觉和嗅觉感觉反应,从而影响行为。本文主要集中于秀丽隐杆线虫和果蝇的最新研究工作,描述了将进食状态信息转化为化学感觉神经元反应特性和行为输出变化的神经调节机制。

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