从高尔基体到细胞表面的货物载体。
Cargo carriers from the Golgi to the cell surface.
机构信息
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.
出版信息
EMBO J. 2012 Oct 17;31(20):3954-5. doi: 10.1038/emboj.2012.249. Epub 2012 Aug 31.
Abstract
In this issue, Malhotra and colleagues use biochemical approaches to identify a new class of secretory cargo carriers (CARTS) that do not contain the larger cargoes, collagen or Vesicular stomatitis virus (VSV)-G glycoprotein. CARTS appear to be basolateral membrane-directed carriers that use myosin for their motility but not for their formation.
摘要
在本期中，Malhotra 及其同事使用生化方法鉴定了一类新的分泌货物载体 (CARTS)，这些载体不包含较大的货物，如胶原蛋白或 Vesicular stomatitis virus (VSV)-G 糖蛋白。CARTS 似乎是基底外侧膜定向载体，它们使用肌球蛋白进行运动，但不用于其形成。
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