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CMV Colitis: A Rare Complication of Azacitidine and Venetoclax Chemotherapy.巨细胞病毒结肠炎：阿扎胞苷和维奈克拉化疗的一种罕见并发症。
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本文引用的文献

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Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia.阿扎胞苷相较于传统治疗方案可延长低骨髓原始细胞计数的老年急性髓系白血病患者的总生存期。
J Clin Oncol. 2010 Feb 1;28(4):562-9. doi: 10.1200/JCO.2009.23.8329. Epub 2009 Dec 21.
2
Antiviral prophylaxis in haematological patients: systematic review and meta-analysis.血液系统疾病患者的抗病毒预防：系统评价和荟萃分析。
Eur J Cancer. 2009 Dec;45(18):3131-48. doi: 10.1016/j.ejca.2009.08.010. Epub 2009 Sep 30.
3
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.阿扎胞苷与传统治疗方案治疗高危骨髓增生异常综合征的疗效比较：一项随机、开放标签的III期研究。
Lancet Oncol. 2009 Mar;10(3):223-32. doi: 10.1016/S1470-2045(09)70003-8. Epub 2009 Feb 21.
4
Cytomegalovirus infection in children who underwent hematopoietic stem cell transplantation at a single center: a retrospective study of the risk factors.单中心接受造血干细胞移植儿童的巨细胞病毒感染：危险因素的回顾性研究
Pediatr Transplant. 2009 Nov;13(7):898-905. doi: 10.1111/j.1399-3046.2008.01084.x. Epub 2008 Nov 18.
5
CMV infections after hematopoietic stem cell transplantation.造血干细胞移植后的巨细胞病毒感染
Bone Marrow Transplant. 2008 Aug;42 Suppl 1:S70-S72. doi: 10.1038/bmt.2008.120.
6
Primary CMV colitis in an immunocompetent infant, successfully treated by gancyclovir.免疫功能正常婴儿的原发性巨细胞病毒性结肠炎，经更昔洛韦成功治疗。
J Pediatr Gastroenterol Nutr. 2008 Aug;47(2):203-5. doi: 10.1097/MPG.0b013e318174e82a.
7
[Case of cytomegalovirus colitis during standard chemotherapy for testicular cancer].
Nihon Hinyokika Gakkai Zasshi. 2008 Mar;99(3):551-4. doi: 10.5980/jpnjurol1989.99.551.
8
Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine.二甲基亚砜和5-氮杂-2'-脱氧胞苷对巨细胞病毒启动子的细胞类型特异性激活作用
Int J Biochem Cell Biol. 2008;40(9):1944-55. doi: 10.1016/j.biocel.2008.02.014. Epub 2008 Mar 7.
9
Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review.免疫功能正常患者的严重巨细胞病毒感染：一项系统评价
Virol J. 2008 Mar 27;5:47. doi: 10.1186/1743-422X-5-47.
10
Detection of cytomegalovirus reactivation in cancer patients receiving chemotherapy.接受化疗的癌症患者中巨细胞病毒再激活的检测。
Clin Microbiol Infect. 2008 Mar;14(3):221-7. doi: 10.1111/j.1469-0691.2007.01895.x. Epub 2007 Dec 5.

阿扎胞苷治疗后巨细胞病毒性结肠炎。

Cytomegalovirus colitis following azacitidine therapy.

机构信息

Department of Internal Medicine;

出版信息

Can J Infect Dis Med Microbiol. 2011 Fall;22(3):e21-3. doi: 10.1155/2011/616725.

DOI:10.1155/2011/616725
PMID:22942891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3200377/
Abstract

The present report describes the first recognized case of cytomegalovirus (CMV) colitis following azacitidine therapy. A 66-year-old woman with myelodysplastic syndrome developed CMV colitis, which responded to treatment with ganciclovir. Currently, patients receiving azacitidine do not undergo CMV testing, or receive prophylaxis or CMV-free blood products; however, this policy needs to be revised.

摘要

本报告描述了首例阿扎胞苷治疗后巨细胞病毒（CMV）结肠炎。一名 66 岁女性患有骨髓增生异常综合征，发生 CMV 结肠炎，经更昔洛韦治疗后缓解。目前，接受阿扎胞苷治疗的患者不进行 CMV 检测，也不接受预防治疗或使用无 CMV 的血液制品；但该策略需要进行修订。