Department of Internal Medicine;
Can J Infect Dis Med Microbiol. 2011 Fall;22(3):e21-3. doi: 10.1155/2011/616725.
The present report describes the first recognized case of cytomegalovirus (CMV) colitis following azacitidine therapy. A 66-year-old woman with myelodysplastic syndrome developed CMV colitis, which responded to treatment with ganciclovir. Currently, patients receiving azacitidine do not undergo CMV testing, or receive prophylaxis or CMV-free blood products; however, this policy needs to be revised.
本报告描述了首例阿扎胞苷治疗后巨细胞病毒(CMV)结肠炎。一名 66 岁女性患有骨髓增生异常综合征,发生 CMV 结肠炎,经更昔洛韦治疗后缓解。目前,接受阿扎胞苷治疗的患者不进行 CMV 检测,也不接受预防治疗或使用无 CMV 的血液制品;但该策略需要进行修订。