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一名复发急性髓系白血病患者在全身化疗后,巨细胞病毒性结肠炎伪装成苹果核样病变。

Cytomegalovirus Colitis Masquerading as Apple-Core Lesion after Systemic Chemotherapy in a Patient with Relapsed Acute Myeloid Leukemia.

作者信息

An Jong, Brownell Jason, Barker Darrell, Stockinger Theresa, Brady Robert, Cebe Katherine, Baur Russell

机构信息

Department of Hematology and Oncology Service, San Antonio Military Medical Center, Fort Sam Houston, San Antonio, TX 78234, USA.

Department of Internal Medicine, San Antonio Military Medical Center, Fort Sam Houston, San Antonio, TX 78234, USA.

出版信息

Case Rep Oncol Med. 2018 Mar 20;2018:5683417. doi: 10.1155/2018/5683417. eCollection 2018.

Abstract

We report the case of a 71-year-old male with relapsed acute myeloid leukemia who developed cytomegalovirus (CMV) colitis presenting as an apple-core lesion during induction chemotherapy. CMV infection occurs rarely during induction chemotherapy for acute myeloid leukemia. CMV infection is usually observed in patients with acquired immune deficiency syndrome (AIDS) and in those on immunosuppressive agents following bone marrow transplant. Although rare, CMV colitis should be considered in patients who are critically ill after systemic chemotherapy as it can cause significant morbidity and mortality.

摘要

我们报告了一例71岁复发急性髓系白血病男性患者,其在诱导化疗期间发生巨细胞病毒(CMV)结肠炎,表现为苹果核样病变。CMV感染在急性髓系白血病诱导化疗期间很少发生。CMV感染通常见于获得性免疫缺陷综合征(AIDS)患者以及骨髓移植后使用免疫抑制剂的患者。尽管罕见,但对于全身化疗后病情危重的患者应考虑CMV结肠炎,因为它可导致显著的发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cdb/5884229/ebd52db310d1/CRIONM2018-5683417.001.jpg

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