Bridge J A, Borek D A, Neff J R, Huntrakoon M
Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City 66103.
Am J Clin Pathol. 1990 Jan;93(1):26-31. doi: 10.1093/ajcp/93.1.26.
Cytogenetic analysis was performed on three specimens of clear cell sarcoma, a rare neoplasm of uncertain histogenesis. Chromosomal analysis of clear cell sarcoma has not been reported previously. Two of the specimens analyzed consisted of the primary foot lesion and subsequent lymph node metastasis in a 29-year-old male. The other specimen was a primary foot lesion in a 61-year-old male. Clonal abnormalities were detected in all three of the specimens. The significance of these results with regard to the origin of this uncommon neoplasm is discussed.
对三例透明细胞肉瘤标本进行了细胞遗传学分析，透明细胞肉瘤是一种组织发生不明的罕见肿瘤。此前尚未有透明细胞肉瘤的染色体分析报告。其中两例分析标本包括一名29岁男性的足部原发性病变及随后的淋巴结转移。另一例标本是一名61岁男性的足部原发性病变。在所有三例标本中均检测到克隆性异常。本文讨论了这些结果对于这种罕见肿瘤起源的意义。
