Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin 541006, China.
Fitoterapia. 2012 Dec;83(8):1489-93. doi: 10.1016/j.fitote.2012.08.015. Epub 2012 Aug 29.
A new cardenolide tupichinolide (1) and a new steroidal saponin tupichinin A (2), together with seven known compounds, were isolated from the rhizomes of Tupistra chinensis. Their structures were established using spectroscopic analysis and chemical methods. Compound 1 was the first cardenolide isolated from Tupistra chinensis and exhibited potent cytotoxicity against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480.
从中国兜兰（Tupistra chinensis）的根茎中分离得到一个新的卡烯内酯化合物 tupichinolide（1）和一个新的甾体皂苷化合物 tupichinin A（2），以及另外七个已知化合物。采用光谱分析和化学方法确定了它们的结构。化合物 1 是从中国兜兰中分离得到的第一个卡烯内酯，对五种人癌细胞系（HL-60、SMMC-7721、A-549、MCF-7 和 SW480）具有很强的细胞毒性。
