Public Health Agency, Health Protection Division, Belfast, UK.
J Hosp Infect. 2012 Oct;82(2):125-8. doi: 10.1016/j.jhin.2012.07.011. Epub 2012 Sep 1.
The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.
本研究通过与其他已知暴发菌株进行比较，来研究与艰难梭菌 078 型相关的发病率和死亡率。与 027 型相比，在阳性标本后 8 周内发生的医疗保健交互作用显著增加了 078 型的可能性。078 型的个体也倾向于来自社区来源，与 027 型相比，标本后的住院时间相似，30 天死亡率较低，但这些差异没有统计学意义。本研究提出了几个假设和一种方法学平台来探索这种独特的模式。
