Department of Pediatrics, University of Vermont, FAHC-Smith 556, Burlington, VT 05401, USA.
Clin Perinatol. 2012 Sep;39(3):459-81. doi: 10.1016/j.clp.2012.06.015.
This article explores the potential benefits and risks for the various approaches to the initial respiratory management of preterm infants. The authors focus on the evidence for the increasingly used strategies of initial respiratory support of preterm infants with continuous positive airway pressure (CPAP) beginning in the delivery room or very early in the hospital course and blended strategies involving the early administration of surfactant replacement followed by immediate extubation and stabilization on CPAP. Where possible, the evidence referenced in this review comes from individual randomized controlled trials or meta-analyses of those trials.
本文探讨了早产儿初始呼吸管理的各种方法的潜在益处和风险。作者重点介绍了在产房或住院早期开始使用持续气道正压通气（CPAP）为早产儿提供初始呼吸支持的越来越多的策略的证据，以及涉及早期给予表面活性剂替代物、随后立即拔管并在 CPAP 上稳定的混合策略。在可能的情况下，本综述中引用的证据来自于单独的随机对照试验或这些试验的荟萃分析。
