日本用于增强受血者血液警戒的输血相关不良事件在线报告系统：一项试点研究。

Online reporting system for transfusion-related adverse events to enhance recipient haemovigilance in Japan: a pilot study.

作者信息

Odaka Chikako, Kato Hidefumi, Otsubo Hiroko, Takamoto Shigeru, Okada Yoshiaki, Taneichi Maiko, Okuma Kazu, Sagawa Kimitaka, Hoshi Yasutaka, Tasaki Tetsunori, Fujii Yasuhiko, Yonemura Yuji, Iwao Noriaki, Tanaka Asashi, Okazaki Hitoshi, Momose Shun-Ya, Kitazawa Junichi, Mori Hiroshi, Matsushita Akio, Nomura Hisako, Yasoshima Hitoshi, Ohkusa Yasushi, Yamaguchi Kazunari, Hamaguchi Isao

机构信息

Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.

出版信息

Transfus Apher Sci. 2013 Feb;48(1):95-102. doi: 10.1016/j.transci.2012.07.008. Epub 2012 Sep 3.

DOI:10.1016/j.transci.2012.07.008

PMID:22954634

Abstract

BACKGROUND

A surveillance system for transfusion-related adverse reactions and infectious diseases in Japan was started at a national level in 1993, but current reporting of events in recipients is performed on a voluntary basis. A reporting system which can collect information on all transfusion-related events in recipients is required in Japan.

METHODS

We have developed an online reporting system for transfusion-related events and performed a pilot study in 12 hospitals from 2007 to 2010.

RESULTS

The overall incidence of adverse events per transfusion bag was 1.47%. Platelet concentrates gave rise to statistically more adverse events (4.16%) than red blood cells (0.66%) and fresh-frozen plasma (0.93%). In addition, we found that the incidence of adverse events varied between hospitals according to their size and patient characteristics.

CONCLUSION

This online reporting system is useful for collection and analysis of actual adverse events in recipients of blood transfusions and may contribute to enhancement of the existing surveillance system for recipients in Japan.

摘要