Odaka Chikako, Kato Hidefumi, Otsubo Hiroko, Takamoto Shigeru, Okada Yoshiaki, Taneichi Maiko, Okuma Kazu, Sagawa Kimitaka, Hoshi Yasutaka, Tasaki Tetsunori, Fujii Yasuhiko, Yonemura Yuji, Iwao Noriaki, Tanaka Asashi, Okazaki Hitoshi, Momose Shun-Ya, Kitazawa Junichi, Mori Hiroshi, Matsushita Akio, Nomura Hisako, Yasoshima Hitoshi, Ohkusa Yasushi, Yamaguchi Kazunari, Hamaguchi Isao
Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.
Transfus Apher Sci. 2013 Feb;48(1):95-102. doi: 10.1016/j.transci.2012.07.008. Epub 2012 Sep 3.
A surveillance system for transfusion-related adverse reactions and infectious diseases in Japan was started at a national level in 1993, but current reporting of events in recipients is performed on a voluntary basis. A reporting system which can collect information on all transfusion-related events in recipients is required in Japan.
We have developed an online reporting system for transfusion-related events and performed a pilot study in 12 hospitals from 2007 to 2010.
The overall incidence of adverse events per transfusion bag was 1.47%. Platelet concentrates gave rise to statistically more adverse events (4.16%) than red blood cells (0.66%) and fresh-frozen plasma (0.93%). In addition, we found that the incidence of adverse events varied between hospitals according to their size and patient characteristics.
This online reporting system is useful for collection and analysis of actual adverse events in recipients of blood transfusions and may contribute to enhancement of the existing surveillance system for recipients in Japan.
日本于1993年启动了全国范围内输血相关不良反应和传染病监测系统，但目前对受血者事件的报告是自愿进行的。日本需要一个能够收集受血者所有输血相关事件信息的报告系统。
我们开发了一个输血相关事件在线报告系统，并于2007年至2010年在12家医院进行了试点研究。
每袋输血的不良事件总发生率为1.47%。血小板浓缩液引发的不良事件（4.16%）在统计学上比红细胞（0.66%）和新鲜冰冻血浆（0.93%）更多。此外，我们发现不同医院的不良事件发生率因医院规模和患者特征而异。
这个在线报告系统有助于收集和分析输血受血者实际发生的不良事件，并可能有助于加强日本现有的受血者监测系统。
