Autism Speaks, New York, NY, USA.
J Neurodev Disord. 2012 May 17;4(1):11. doi: 10.1186/1866-1955-4-11.
For decades, researchers have sought to clarify the nature of the social communication impairments in autism, highlighting impaired or atypical 'social attention' as a key measurable construct that helps to define the core impairment of social communication. In this paper, we provide an overview of research on social attention impairments in autism and their relation to deficiencies in neural circuitry related to social reward. We offer a framework for considering social attention as a potential moderator or mediator of response to early behavioral intervention, and as an early indicator of efficacy of behavioral and/or pharmacological treatments aimed at addressing the social impairments in autism.
几十年来，研究人员一直试图阐明自闭症患者社会交往障碍的性质，强调受损或异常的“社会注意力”作为一个关键的可衡量结构，有助于定义社会交往核心障碍。在本文中，我们提供了一个自闭症患者社会注意力障碍及其与社会奖励相关神经回路缺陷关系的研究综述。我们提供了一个框架，将社会注意力作为对早期行为干预反应的潜在调节或中介因素，并作为行为和/或药物治疗针对自闭症社会障碍的疗效的早期指标。
