印度北部被低估的滥用药物：卡利他醇。
Carisoprodol: an underrecognized drug of abuse in north India.
机构信息
Department of Psychiatry, Postgraduate Institute Medical Science, Rohtak, Haryana, 124001, India.
出版信息
Gen Hosp Psychiatry. 2013 Jan-Feb;35(1):89-92. doi: 10.1016/j.genhosppsych.2012.07.011. Epub 2012 Sep 5.
BACKGROUND
There is limited literature on clinical profile of subjects abusing carisoprodol.
METHODS
Our series of 34 subjects shows that a typical subject was an unmarried, unemployed, urban resident from a nuclear family set up; was a substance abuser before being introduced to carisoprodol by another substance abuser; initiated the use to get a better "kick" and after regular use reported craving and withdrawal symptoms.
RESULTS
The effect of carisoprodol was dose dependent: a majority reported a feeling of general wellbeing on consuming up to three tablets; a hypomanic state with 4-10 tablets and confusion, disorientation and drowsiness with >10 tablets at a time.
CONCLUSION
Thus being an underrecognized drug of abuse, carisoprodol is in need of wider awareness and regulatory measures to prevent its emergence as a greater menace in the future.
背景
关于滥用卡利曲朵的患者的临床特征，目前相关文献有限。
方法
我们的 34 例患者系列研究表明，典型的滥用者为未婚、失业的城市居民，来自核心家庭；在被其他药物滥用者介绍使用卡利曲朵之前就已经是药物滥用者；开始使用是为了获得更好的“快感”，并且在常规使用后报告出现渴望和戒断症状。
结果
卡利曲朵的效果与剂量有关：大多数患者在服用三粒以内会有全身舒适的感觉；服用 4-10 粒时会出现轻躁狂状态，服用超过 10 粒时会出现意识混乱、定向障碍和嗜睡。
结论
因此，作为一种未被充分认识的滥用药物，卡利曲朵需要更广泛的认识和监管措施，以防止其在未来成为更大的威胁。
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