酒精戒断所致帕金森综合征：一项随访研究。
Parkinsonism in alcohol withdrawal: a follow-up study.
作者信息
Shandling M, Carlen P L, Lang A E
机构信息
Division of Neurology, Mt. Sinai Hospital, University of Toronto, Ontario, Canada.
出版信息
Mov Disord. 1990;5(1):36-9. doi: 10.1002/mds.870050109.
Transient parkinsonism associated with alcohol intake and withdrawal has previously been described. We followed-up three patients with acute alcohol withdrawal-induced parkinsonism 9-11 years after their initial presentation. None showed any evidence of parkinsonism at follow-up. This suggests that withdrawal-induced parkinsonism is caused by a completely reversible abnormality in nigrostriatal dopamine transmission, which is unaccompanied by underlying nigral degeneration, as we had previously hypothesized.
此前已有与酒精摄入和戒断相关的短暂性帕金森病的描述。我们对3例急性酒精戒断所致帕金森病患者在首次发病后9 - 11年进行了随访。随访时均未显示出帕金森病的任何证据。这表明戒断所致帕金森病是由黑质纹状体多巴胺传递中完全可逆的异常引起的，正如我们之前所假设的，这种异常并未伴有潜在的黑质变性。
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