锇催化 N-(4-甲苯磺酰氧基)氨基甲酸酯的烯烃邻位氧胺化反应。
Osmium-catalyzed vicinal oxyamination of alkenes by N-(4-toluenesulfonyloxy)carbamates.
机构信息
Research School of Chemistry, Australian National University, Canberra ACT 0200, Australia.
出版信息
J Org Chem. 2012 Oct 5;77(19):8480-91. doi: 10.1021/jo301372y. Epub 2012 Sep 24.
PMID:22963548
Abstract
N-(4-toluenesulfonyloxy)carbamates based on a range of common amine protecting groups serve as preformed nitrogen sources in the intermolecular osmium-catalyzed oxyamination reaction of a variety of mono-, di-, and trisubstituted alkenes. The reactions occur with low catalyst loadings and good yields and afford high regioselectivity for unsymmetrically substituted alkenes.
摘要
基于一系列常见胺保护基的 N-(4-甲苯磺酰氧基)氨基甲酸酯作为预形成的氮源，在各种单取代、二取代和三取代烯烃的分子间锇催化的氧化氨化反应中使用。这些反应在低催化剂负载量和良好收率下进行，并对不对称取代的烯烃具有高区域选择性。
Zotero 插件