• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

白细胞介素-2治疗并发的短暂性局灶性神经功能缺损

Transient focal neurologic deficits complicating interleukin-2 therapy.

作者信息

Bernard J T, Ameriso S, Kempf R A, Rosen P, Mitchell M S, Fisher M

机构信息

Department of Neurology, University of Southern California School of Medicine, Los Angeles 90033.

出版信息

Neurology. 1990 Jan;40(1):154-5. doi: 10.1212/wnl.40.1.154.

DOI:10.1212/wnl.40.1.154
PMID:2296362
Abstract

We report 2 patients with transient, focal, repetitive, stereotyped episodes of neurologic deficits during treatment with interleukin-2. One patient had recurrent monocular blindness, while the 2nd had recurrent homonymous quadrantanopia. We suggest that these attacks are provoked by endothelial cell activation induced by interleukin-2.

摘要

我们报告了2例在接受白细胞介素-2治疗期间出现短暂性、局灶性、重复性、刻板性神经功能缺损发作的患者。1例患者反复出现单眼失明,而第2例患者反复出现同侧象限盲。我们认为这些发作是由白细胞介素-2诱导的内皮细胞活化所引发的。

相似文献

1
Transient focal neurologic deficits complicating interleukin-2 therapy.白细胞介素-2治疗并发的短暂性局灶性神经功能缺损
Neurology. 1990 Jan;40(1):154-5. doi: 10.1212/wnl.40.1.154.
2
The terminology of transient visual loss due to vascular insufficiency.因血管供血不足导致的短暂性视力丧失的术语。
Stroke. 1984 Sep-Oct;15(5):907-8. doi: 10.1161/01.str.15.5.907.
3
Unruptured cerebral aneurysms presenting as recurrent transient neurologic deficits.表现为反复短暂性神经功能缺损的未破裂脑动脉瘤。
Neurology. 1980 Jan;30(1):47-51. doi: 10.1212/wnl.30.1.47.
4
Multiple cerebral lesions complicating therapy with interleukin-2.白细胞介素-2治疗引发的多发性脑损伤
Neurology. 1996 Aug;47(2):417-24. doi: 10.1212/wnl.47.2.417.
5
[Transient monocular blindness: Vascular causes and differential diagnoses].[一过性单眼盲:血管性病因及鉴别诊断]
J Fr Ophtalmol. 2018 May;41(5):453-461. doi: 10.1016/j.jfo.2017.06.027.
6
[A case of giant meningioma that induced visual changes similar to those observed in amaurosis fugax in an early stage of disease].[一例巨大脑膜瘤在疾病早期诱发类似一过性黑矇所见视觉改变的病例]
Rinsho Shinkeigaku. 1999 May;39(5):577-80.
7
Transient visual obscurations, without papilloedema.短暂性视力模糊,无视乳头水肿。
J Neurol Neurosurg Psychiatry. 1982 Sep;45(9):832-4. doi: 10.1136/jnnp.45.9.832.
8
[Focal neurologic manifestations in the course of iatrogenic hypercalcemia].[医源性高钙血症过程中的局灶性神经表现]
Rev Neurol (Paris). 1971 Jul;125(1):15-24.
9
Vasospastic transient monocular visual loss: effect of treatment with different doses of nifedipine.血管痉挛性一过性单眼视力丧失:不同剂量硝苯地平治疗的效果
J Neuroophthalmol. 2014 Dec;34(4):386-8. doi: 10.1097/WNO.0000000000000144.
10
Ocular manifestations of carotid artery atheroma.
J Vasc Surg. 1985 Nov;2(6):850-3.

引用本文的文献

1
In vivo relationship of interleukin-2 and soluble IL-2 receptor to blood-brain barrier impairment in patients with active multiple sclerosis.活动性多发性硬化症患者体内白细胞介素-2及可溶性白细胞介素-2受体与血脑屏障损伤的关系
J Neurol. 1993 Jan;240(1):46-50. doi: 10.1007/BF00838446.
2
Delayed neurotoxicity of intraventricular interleukin-2: a case report.脑室内注射白细胞介素-2的迟发性神经毒性:一例报告
J Neurooncol. 1993 Mar;15(3):265-7. doi: 10.1007/BF01050073.
3
Phase II study of low dose cyclophosphamide and intravenous interleukin-2 in metastatic renal cancer.
低剂量环磷酰胺与静脉注射白细胞介素-2治疗转移性肾癌的II期研究。
Invest New Drugs. 1994;12(1):35-9. doi: 10.1007/BF00873233.
4
Neurotoxicity of antitumoral IL-2 therapy: evoked cognitive potentials and brain mapping.抗肿瘤白细胞介素-2治疗的神经毒性:诱发性认知电位与脑图谱
Ital J Neurol Sci. 1994 Oct;15(7):341-6. doi: 10.1007/BF02339930.
5
Interleukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer.白细胞介素-2。其药理学特性及在癌症患者中的治疗应用综述。
Drugs. 1993 Sep;46(3):446-514. doi: 10.2165/00003495-199346030-00009.
6
Clinical toxicity of interleukin-2.白细胞介素-2的临床毒性
Drug Saf. 1992 Nov-Dec;7(6):417-33. doi: 10.2165/00002018-199207060-00004.