白细胞介素-2治疗并发的短暂性局灶性神经功能缺损
Transient focal neurologic deficits complicating interleukin-2 therapy.
作者信息
Bernard J T, Ameriso S, Kempf R A, Rosen P, Mitchell M S, Fisher M
机构信息
Department of Neurology, University of Southern California School of Medicine, Los Angeles 90033.
出版信息
Neurology. 1990 Jan;40(1):154-5. doi: 10.1212/wnl.40.1.154.
PMID:2296362
Abstract
We report 2 patients with transient, focal, repetitive, stereotyped episodes of neurologic deficits during treatment with interleukin-2. One patient had recurrent monocular blindness, while the 2nd had recurrent homonymous quadrantanopia. We suggest that these attacks are provoked by endothelial cell activation induced by interleukin-2.
摘要
我们报告了2例在接受白细胞介素-2治疗期间出现短暂性、局灶性、重复性、刻板性神经功能缺损发作的患者。1例患者反复出现单眼失明，而第2例患者反复出现同侧象限盲。我们认为这些发作是由白细胞介素-2诱导的内皮细胞活化所引发的。
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