Schwartzman R J, Kerrigan J
Department of Neurology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA.
Neurology. 1990 Jan;40(1):57-61. doi: 10.1212/wnl.40.1.57.
We present 43 patients with reflex sympathetic dystrophy (RSD) who manifested abnormalities of movement. The patients have focal dystonia, weakness, spasms, tremor, difficulty initiating movement, and increased tone and reflexes. These motor signs and symptoms may precede other manifestations of the illness by weeks or months. They most frequently, but not invariably, occur concomitantly with sudomotor or vasomotor changes and pain. Lioresal is effective in reducing spasms. Early in the course of RSD, the motor manifestation may be alleviated by intense sympathetic blockade or sympathectomy. In many patients, the movement disorder becomes independent of sympathetic innervation.
我们报告了43例患有反射性交感神经营养不良(RSD)且有运动异常表现的患者。这些患者存在局灶性肌张力障碍、无力、痉挛、震颤、运动起始困难以及肌张力和反射增强。这些运动体征和症状可能在疾病的其他表现出现前数周或数月就已出现。它们最常(但并非总是)与汗腺运动或血管运动变化及疼痛同时发生。氯苯氨丁酸在减轻痉挛方面有效。在RSD病程早期,强烈的交感神经阻滞或交感神经切除术可能会缓解运动表现。在许多患者中,运动障碍会变得与交感神经支配无关。