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经口咽入路舌体消融术治疗阻塞性睡眠呼吸暂停低通气综合征。

Tongue coblation via the ventral approach for obstructive sleep apnea-hypopnea syndrome surgery.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Laryngoscope. 2012 Nov;122(11):2582-6. doi: 10.1002/lary.23556. Epub 2012 Sep 10.

DOI:10.1002/lary.23556
PMID:22965646
Abstract

OBJECTIVES/HYPOTHESIS: To determine the safety and efficacy of tongue Coblation via the ventral approach in the treatment of hypopharyngeal obstruction for patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).

STUDY DESIGN

Prospective case-control study.

METHODS

Tongue Coblation was performed under local anesthesia in one session in 40 inpatients diagnosed with OSAHS with predominant hypopharyngeal obstruction after failed uvulopalatopharyngoplasty. In the ventral approach (n = 20), only one puncture point was applied at the center of lingual frenulum, and 12 radiofrequency volumetric tissue reduction (RFVTR) lesions were implanted in the tongue. In the dorsal approach (n = 20), eight RFVTR lesions were distributed on the tongue. Using portable polysomnography (PSG) and the Epworth sleepiness questionnaire (ESQ), we followed 36 patients for 1 year after the operation. Good outcome was defined as apnea-hypopnea index <20 or reduction >50%.

RESULTS

In the ventral approach, total energy was accumulated to 23,000 J in 12 lesions, with postoperative pain 2-3 by visual analog scale (VAS). There was only one case of moderate venous bleeding and hematoma. The ESQ comparison indicated subjective improvements in patients, and PSG showed a curative effect in 11 of 19 (61.11%, eight of 19 success plus three of 19 responders), with a failure rate of eight of 19. By contrast, in the dorsal approach, total energy was 16,000 J, with postoperative pain 3-4 (VAS). Complications included mild to moderate tongue venous hematoma, severe infection of tongue, and temporary mild glossal deviation. A curative effect was seen in six of 17, with a failure rate of 11 of 17.

CONCLUSIONS

Tongue Coblation via the ventral approach is an effective and safe technique to treat hypopharyngeal obstruction in OSAHS surgery.

摘要

目的/假设:确定经腹侧入路行舌 Coblation 治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者咽后阻塞的安全性和有效性。

研究设计

前瞻性病例对照研究。

方法

40 例 OSAHS 伴主要咽后阻塞的住院患者在局部麻醉下一次性行舌 Coblation 治疗。在腹侧入路(n = 20)中,仅在舌系带中心应用一个穿刺点,在舌内植入 12 个射频容积组织减少(RFVTR)病灶。在背侧入路(n = 20)中,将 8 个 RFVTR 病灶分布在舌上。使用便携式多导睡眠图(PSG)和 Epworth 嗜睡量表(ESQ),我们在术后随访了 36 例患者 1 年。良好的结果定义为呼吸暂停低通气指数<20 或减少>50%。

结果

在腹侧入路中,12 个病灶的总能量累积到 23000 J,术后疼痛为 2-3 分(视觉模拟评分法[VAS])。仅有 1 例中度静脉出血和血肿。ESQ 比较表明患者主观改善,19 例中有 11 例(61.11%,8 例成功加 3 例有反应)PSG 显示疗效,19 例中有 8 例失败。相比之下,在背侧入路中,总能量为 16000 J,术后疼痛为 3-4 分(VAS)。并发症包括轻度至中度舌静脉血肿、严重舌感染和暂时性轻度舌偏斜。17 例中有 6 例有效,17 例中有 11 例失败。

结论

经腹侧入路行舌 Coblation 是治疗 OSAHS 手术中咽后阻塞的一种有效且安全的技术。

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