嗜水气单胞菌噬菌体 CC2 的全基因组序列
Complete Genome Sequence of Aeromonas hydrophila Phage CC2.
机构信息
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
出版信息
J Virol. 2012 Oct;86(19):10900. doi: 10.1128/JVI.01882-12.
Abstract
Aeromonas hydrophila is one of the major pathogenic bacteria for fish and people. To develop an effective antimicrobial agent, we isolated a bacteriophage from sewage, named CC2, and sequenced its genome. Comparative genome analysis of phage CC2 with its relatives revealed that phage CC2 has higher sequence homology to A. salmonicida phage 65 than to A. hydrophila phage Aeh1. Here, we announce the complete genome sequence of CC2 and report major findings from the genomic analysis.
摘要
嗜水气单胞菌是鱼类和人类的主要病原菌之一。为了开发一种有效的抗菌剂，我们从污水中分离出一种噬菌体，命名为 CC2，并对其基因组进行了测序。与 CC2 的亲缘关系进行比较基因组分析表明，与 A. hydrophila 噬菌体 Aeh1 相比，噬菌体 CC2 与 A. salmonicida 噬菌体 65 具有更高的序列同源性。在此，我们公布了 CC2 的完整基因组序列，并报告了基因组分析的主要发现。
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