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基于去硅反应探针的体内双光子荧光成像检测氟离子。

In vivo two-photon fluorescent imaging of fluoride with a desilylation-based reactive probe.

机构信息

Department of Chemistry, Center for Electro-Photo Behaviors in Advanced Molecular Systems, POSTECH, San 31, Hyoja-dong, Pohang, 790-784, Republic of Korea.

出版信息

Chem Commun (Camb). 2012 Oct 21;48(82):10243-5. doi: 10.1039/c2cc35668f.

DOI:10.1039/c2cc35668f
PMID:22968490
Abstract

A two-photon excitable molecular probe for fluoride, developed based on a fluoride-specific desilylation reaction, is demonstrated to be useful for fluorescent imaging of fluoride ions in live zebrafish by one-photon as well as two-photon microscopy for the first time.

摘要

一种基于氟离子特异性去硅反应的双光子激发分子探针，首次被证明可用于单光子和双光子显微镜下活斑马鱼中氟离子的荧光成像。

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