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重编程用干细胞:人 UMSC 会不会是更好的选择?

Stem cells for reprogramming: could hUMSCs be a better choice?

机构信息

Tianjin University of Traditional Chinese Medicine, 312 Anshan West Road, Nankai district, Tianjin, China.

出版信息

Cytotechnology. 2013 May;65(3):335-45. doi: 10.1007/s10616-012-9489-3. Epub 2012 Sep 12.

Abstract

Human umbilical cord mesenchymal stem cells (hUMSC) are primitive multipotent cells capable of differentiating into cells of different lineages. They can be an alternative source of pluripotent cells since they are ethically and regulatory approved, are easily obtained and have low immunogenicity compared to embryonic stem cells which are dogged with numerous controversies. hUMSC can be a great source for cell and transplantation therapy.

摘要

人脐带间充质干细胞(hUMSC)是原始的多能细胞,能够分化为不同谱系的细胞。与存在诸多争议的胚胎干细胞相比,它们具有伦理和监管批准、易于获得且免疫原性低等优势,是多能细胞的一种替代来源。hUMSC 可以成为细胞和移植治疗的重要来源。

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