Traditional and Complementary Medicine Research Program, School of Health Sciences and Health Innovations Research Institute-HIRi, RMIT University, Bundoora, Melbourne, Victoria, Australia.
Phytother Res. 2013 Jul;27(7):949-65. doi: 10.1002/ptr.4832. Epub 2012 Sep 12.
Panax ginseng C.A. Meyer is a common herb with many purported health benefits. However, there is no conclusive evidence supporting its use in the treatment of any particular disease. We conducted a systematic review to evaluate randomised controlled trials. Four English databases were searched with no publication date restriction. Included studies evaluated P. ginseng in patients with any type of disease or in healthy individuals. We assessed the quality of studies using the Cochrane risk of bias tool. Of the 475 potentially relevant studies, 65 met the inclusion criteria. These studies examined P. ginseng's effects on psychomotor performance (17 studies), physical performance (ten), circulatory system (eight), glucose metabolism (six), the respiratory system (five), erectile dysfunction (four), immunomodulation (four), quality of life/mood (four), antioxidant function (two), cancer (two), menopausal symptoms (two) and dry mouth (one). The risk of bias was unclear in most studies. Authors evaluated adverse events in 40 studies, with 135 minor events and no serious adverse events reported. P. ginseng shows promising results for improving glucose metabolism and moderating the immune response. This may have implications for several diseases including type 2 diabetes and chronic respiratory conditions. Further studies are needed to explore P. ginseng's potential as an effective treatment for these and other health conditions.
人参是一种常见的草药,据称有许多健康益处。然而,没有确凿的证据支持其用于治疗任何特定疾病。我们进行了系统评价,以评估随机对照试验。四个英文数据库进行了搜索,没有出版日期限制。纳入的研究评估了人参在患有任何类型疾病的患者或健康个体中的作用。我们使用 Cochrane 偏倚风险工具评估了研究的质量。在 475 篇可能相关的研究中,有 65 篇符合纳入标准。这些研究考察了人参对精神运动表现(17 项研究)、身体表现(10 项)、循环系统(8 项)、葡萄糖代谢(6 项)、呼吸系统(5 项)、勃起功能障碍(4 项)、免疫调节(4 项)、生活质量/情绪(4 项)、抗氧化功能(2 项)、癌症(2 项)、更年期症状(2 项)和口干(1 项)的影响。大多数研究的偏倚风险不明确。作者在 40 项研究中评估了不良事件,其中有 135 项轻微事件,没有报告严重不良事件。人参在改善葡萄糖代谢和调节免疫反应方面显示出有前景的结果。这可能对包括 2 型糖尿病和慢性呼吸道疾病在内的几种疾病有影响。需要进一步研究来探索人参作为这些和其他健康状况的有效治疗方法的潜力。