Department of Pediatrics, Gastroenterology Division, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, United States.
World J Gastroenterol. 2012 Sep 7;18(33):4466-9. doi: 10.3748/wjg.v18.i33.4466.
Eosinophilic esophagitis is a newly diagnosed esophageal disease in adult and children. The clinical and pathological characteristics of this disease have been established and were recently summarized in the expert clinical guideline published in 2011. In spite of the wide knowledge accumulated on this disease, there are many areas where scientific data are missing, especially in regard to the disease's pathophysiology. Recent publications have suggested that other confounding factors modify the disease and may affect its clinical-phenotypic presentation. Those factors may include place of living, air pollution, race, genetic factors and other. In the present report we discussed and review those confounding factors, the new developments, and what direction we should go to further advance our knowledge of this disease.
嗜酸性粒细胞性食管炎是一种新诊断的成人和儿童食管疾病。该疾病的临床和病理特征已经确立，并于最近在 2011 年发布的专家临床指南中进行了总结。尽管对这种疾病积累了广泛的知识，但仍有许多领域缺乏科学数据，特别是在疾病的病理生理学方面。最近的出版物表明，其他混杂因素会改变疾病并可能影响其临床表型。这些因素可能包括居住地点、空气污染、种族、遗传因素等。在本报告中，我们讨论和回顾了这些混杂因素、新的发展方向，以及我们应该朝着哪个方向进一步深入了解这种疾病。
