Papasova M, Velkova V, Atanassova E
Acta Physiol Pharmacol Bulg. 1979;5(2):3-10.
Experiments are carried out on six dogs with chronically implanted electrodes in the gastric wall and in the duodenum. The electrical activity of the stomach (EGMG) and of the duodenum (EEG) is recorded. The myoelectrical complex of the stomach consists of four phases. The first phase records only slow potentials and lasts 40--60 min. The appearance of spike activity in the duodenum is always preceded by EGMG activation. Intravenous injection of the specific blocker of the alpha-adrenergic structures (phentolamine -- 1 mg/kg) leads to the appearance of spike activity in EGMG and EEG. 50--60 per cent of the slow waves being accompanied by spike potentials. At the same time the frequency of the slow potentials from EGMG is also decreased. Application of beta-adrenoblocker (propranolol -- 2 mg/kg) does not change subatantially EGMG and EEG. Simultaneous administration of alpha- and beta-adrenoblockers prolongs spiking time in the stomach and duodenum (spike potentials are recorded for 120--180 min, duration in the background 40--50 min). The influence of the interactions of cholinergic and adrenergic structures on the character of EGMG and EEG is discussed.
对六只在胃壁和十二指肠中长期植入电极的狗进行了实验。记录胃（EGMG）和十二指肠（EEG）的电活动。胃的肌电复合波由四个阶段组成。第一阶段仅记录慢电位，持续40 - 60分钟。十二指肠中尖峰活动的出现总是先于EGMG激活。静脉注射α - 肾上腺素能结构的特异性阻断剂（酚妥拉明 - 1毫克/千克）会导致EGMG和EEG中出现尖峰活动。50 - 60%的慢波伴有尖峰电位。同时，EGMG慢电位的频率也降低。应用β - 肾上腺素能阻断剂（普萘洛尔 - 2毫克/千克）对EGMG和EEG没有实质性改变。同时给予α和β肾上腺素能阻断剂会延长胃和十二指肠的尖峰时间（记录到尖峰电位120 - 180分钟，背景持续时间40 - 50分钟）。讨论了胆碱能和肾上腺素能结构相互作用对EGMG和EEG特征的影响。
