学习、记忆与经颅直流电刺激
Learning, memory, and transcranial direct current stimulation.
作者信息
Brasil-Neto Joaquim P
机构信息
Laboratory of Neurosciences and Behavior, Biology Institute, University of Brasília Brasília, Brazil.
出版信息
Front Psychiatry. 2012 Sep 3;3:80. doi: 10.3389/fpsyt.2012.00080. eCollection 2012.
Abstract
Transcranial direct current stimulation (tDCS) has been the subject of many studies concerning its possible cognitive effects. One of the proposed mechanisms of action for neuromodulatory techniques, such as transcranial magnetic stimulation and tDCS is induction of long-term potentiation (LTP) and long-term depression (LTD)-like phenomena. LTP and LTD are also among the most important neurobiological processes involved in memory and learning. This fact has led to an immediate interest in the study of possible effects of tDCS on memory consolidation, retrieval, or learning of various tasks. This review analyses published articles describing beneficial or disruptive effects of tDCS on memory and learning in normal subjects. The most likely mechanisms underlying these effects are discussed.
摘要
经颅直流电刺激（tDCS）一直是众多关于其可能的认知效应研究的主题。神经调节技术，如经颅磁刺激和tDCS，其作用机制之一是诱导长时程增强（LTP）和长时程抑制（LTD）样现象。LTP和LTD也是参与记忆和学习的最重要神经生物学过程之一。这一事实使得人们立即对研究tDCS对各种任务的记忆巩固、检索或学习的可能影响产生了兴趣。这篇综述分析了已发表的描述tDCS对正常受试者记忆和学习的有益或破坏作用的文章。并讨论了这些效应背后最可能的机制。
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