Department of Dermatology, Belfast Health and Social Care Trust, Ulster Hospital Dundonald, Belfast, Down, UK.
Photodermatol Photoimmunol Photomed. 2012 Oct;28(5):258-60. doi: 10.1111/j.1600-0781.2012.00676.x.
The incidence of phototoxicity as a side effect of ciprofloxacin appears to be increased in patients with cystic fibrosis compared to the general population (approximately 2.4%). We used an interview-based questionnaire to determine the incidence of such phototoxic skin reactions in cystic fibrosis patients. Results from 105 respondents revealed the incidence of ciprofloxacin-induced phototoxicity in the adult cystic fibrosis population in Northern Ireland to be 48.4% with only 66% of the patients recalling being given sun care information beforehand. We concluded that the incidence of phototoxicity is increased in patients with cystic fibrosis and that it is important for all to receive good sun care information prior to taking ciprofloxacin given the high risk of developing phototoxic rash.
环丙沙星的光毒性作为一种副作用，在囊性纤维化患者中的发生率似乎比普通人群（约 2.4%）更高。我们使用基于访谈的问卷来确定囊性纤维化患者中这种光毒性皮肤反应的发生率。105 名受访者的结果显示，北爱尔兰成年囊性纤维化人群中，环丙沙星引起的光毒性发生率为 48.4%，只有 66%的患者事先记得接受过防晒信息。我们得出结论，囊性纤维化患者的光毒性发生率增加，鉴于发生光毒性皮疹的风险很高，在服用环丙沙星之前，所有患者都应获得良好的防晒信息。
