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海洋来源真菌杂色曲霉EN-7产生的蒽醌衍生物。

Anthraquinone derivatives produced by marine-derived fungus Aspergillus versicolor EN-7.

作者信息

Zhang Yi, Li Xiao-Ming, Wang Bin-Gui

机构信息

Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, People's Republic of China.

出版信息

Biosci Biotechnol Biochem. 2012;76(9):1774-6. doi: 10.1271/bbb.120047. Epub 2012 Sep 7.

DOI:10.1271/bbb.120047
PMID:22972319
Abstract

The new anthraquinone derivative, 6,8-di-O-methylaverantin (1), together with six known congeners (2-7), were characterized from a culture extract of the marine algous fungus, Aspergillus versicolor EN-7. Their structures were elucidated by spectroscopic methods. A bioassay showed compounds 1, 2 and 5 to have weak inhibition against Escherichia coli, while compound 5 also displayed weak inhibition against Staphylococcus aureus.

摘要

从海洋藻类真菌杂色曲霉EN-7的培养提取物中鉴定出新型蒽醌衍生物6,8-二-O-甲基averantin（1）以及六种已知的同系物（2-7）。通过光谱方法阐明了它们的结构。生物测定表明化合物1、2和5对大肠杆菌具有微弱抑制作用，而化合物5对金黄色葡萄球菌也表现出微弱抑制作用。

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