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来自特异青霉属菌株YO-2的新曲霉二萜类同系物,曲霉二萜D-H

New chrodrimanin congeners, chrodrimanins D-H, from YO-2 of Talaromyces sp.

作者信息

Hayashi Hideo, Oka Yuki, Kai Kenji, Akiyama Kohki

机构信息

Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.

出版信息

Biosci Biotechnol Biochem. 2012;76(9):1765-8. doi: 10.1271/bbb.120365. Epub 2012 Sep 7.

DOI:10.1271/bbb.120365
PMID:22972343
Abstract

Four new meroterpenoids, named chrodrimanins D-G (4-7), and one known compound, renamed chrodrimanin H (8), were isolated from okara (the insoluble residue of whole soybean) that had been fermented with the YO-2 strain of Talaromyces sp. Their structures were elucidated by spectroscopic methods. Chrodrimanins D (4), E (5), and F (6) showed insecticidal activity against silkworms with respective LD(50) values of 20, 10, and 50 µg/g of diet.

摘要

从用特异青霉属YO - 2菌株发酵的豆渣(全大豆的不溶性残渣)中分离出4种新的半萜类化合物,命名为chrodrimanins D - G(4 - 7),以及1种已知化合物,重新命名为chrodrimanin H(8)。通过光谱方法阐明了它们的结构。Chrodrimanins D(4)、E(5)和F(6)对家蚕表现出杀虫活性,其半数致死剂量(LD50)分别为每克饲料20、10和50微克。

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