Saudny Helga, Cao Zhirong, Egeland Grace M
Centre for Indigenous Peoples' Nutrition and Environment, School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada.
Int J Circumpolar Health. 2012;71. doi: 10.3402/ijch.v71i0.18589. Epub 2012 Aug 22.
To determine the extent to which demographic characteristics, clinical measurements and biomarkers were associated with poor self-reported health (SRH) among Inuit adults in the Canadian Arctic.
Cross-sectional survey was adopted as the study design.
The International Polar Year Inuit Health Survey carried out in 36 Canadian Arctic communities in 2007 and 2008 included Inuit men and women, aged 18 years or older, recruited from randomly selected households. The main outcome measure was SRH, which was dichotomized into good health (excellent, very good and good responses) and poor health (fair and poor responses).
Of the 2,796 eligible households, 1,901 (68%) households and 2,595 participants took part in the survey. The weighted prevalence of poor SRH was 27.8%. Increasing age was significantly associated with poor SRH. The relative risk ratios for poor SRH was 2.0 (95% confidence interval [CI] 1.3-3.1) for men aged 50 years or older and 2.3 (95% CI 1.7-3.0) for women aged 50 years or older, compared with men and women aged 29 years or younger. After adjusting for age, gender and body mass index, poor SRH was significantly associated with smoking status (odds ratio [OR]=1.5; CI 1.1-2.0), at-risk fasting glucose levels (≥ 6.1 mmol/L) (OR=2.5; 95%; CI 1.5-4.2) and elevated hs C-reactive protein levels (>3-≤ 10 mg/L) (OR=2.1; 95% CI 1.4-3.1). Poor SRH was also significantly associated with a hypertriglyceridemic waist phenotype (high-risk waist circumference ≥ 102 cm for men and ≥ 88 cm for women with high triglyceride levels, ≥ 1.7 mmol/L), adjusted for age and gender, OR=1.6; 95% CI 1.1-2.3.
Clinically relevant indicators of chronic disease risk were related to subjective assessment of SRH among Inuit.
确定在加拿大北极地区的因纽特成年人中，人口统计学特征、临床测量指标和生物标志物与自我报告健康状况不佳（SRH）之间的关联程度。
采用横断面调查作为研究设计。
2007年和2008年在加拿大北极地区36个社区开展的国际极地年因纽特人健康调查，纳入了从随机选择的家庭中招募的18岁及以上的因纽特男性和女性。主要结局指标是SRH，分为健康状况良好（优秀、非常好和好的回答）和健康状况不佳（一般和差的回答）。
在2796个符合条件的家庭中，1901个（68%）家庭和2595名参与者参与了调查。自我报告健康状况不佳的加权患病率为27.8%。年龄增长与自我报告健康状况不佳显著相关。与29岁及以下的男性和女性相比，50岁及以上男性自我报告健康状况不佳的相对风险比为2.0（95%置信区间[CI]1.3 - 3.1），50岁及以上女性为2.3（95%CI 1.7 - 3.0）。在调整年龄、性别和体重指数后，自我报告健康状况不佳与吸烟状况（优势比[OR]=1.5；CI 1.1 - 2.0）、空腹血糖风险水平（≥6.1 mmol/L）（OR=2.5；95%；CI 1.5 - 4.2）和hs-C反应蛋白水平升高（>3 - ≤10 mg/L）（OR=2.1；95%CI 1.4 - 3.1）显著相关。在调整年龄和性别后，自我报告健康状况不佳也与高甘油三酯腰围表型（男性高风险腰围≥102 cm，女性甘油三酯水平≥1.7 mmol/L时腰围≥88 cm）显著相关，OR=1.6；95%CI 1.1 - 2.3。
慢性病风险的临床相关指标与因纽特人自我报告健康状况的主观评估有关。
