儿童哮喘的呼吸道病毒感染：它们重要吗？我们能预防它们吗？
Respiratory viral infections in children with asthma: do they matter and can we prevent them?
机构信息
The Queensland Children's Medical Research Institute, The University of Queensland, Brisbane, Australia.
出版信息
BMC Pediatr. 2012 Sep 13;12:147. doi: 10.1186/1471-2431-12-147.
BACKGROUND
Asthma is a major public health problem with a huge social and economic burden affecting 300 million people worldwide. Viral respiratory infections are the major cause of acute asthma exacerbations and may contribute to asthma inception in high risk young children with susceptible genetic background. Acute exacerbations are associated with decreased lung growth or accelerated loss of lung function and, as such, add substantially to both the cost and morbidity associated with asthma.
DISCUSSION
While the importance of preventing viral infection is well established, preventive strategies have not been well explored. Good personal hygiene, hand-washing and avoidance of cigarette smoke are likely to reduce respiratory viral infections. Eating a healthy balanced diet, active probiotic supplements and bacterial-derived products, such as OM-85, may reduce recurrent infections in susceptible children. There are no practical anti-viral therapies currently available that are suitable for widespread use.
SUMMARY
Hand hygiene is the best measure to prevent the common cold. A healthy balanced diet, active probiotic supplements and immunostimulant OM-85 may reduce recurrent infections in asthmatic children.
背景
哮喘是一个重大的公共卫生问题，在全球范围内影响着 3 亿人，给社会和经济带来了巨大的负担。呼吸道病毒感染是急性哮喘加重的主要原因，并且可能导致具有易感遗传背景的高危幼儿发生哮喘。急性加重与肺生长减少或肺功能加速丧失有关，因此会大大增加与哮喘相关的成本和发病率。
讨论
虽然预防病毒感染的重要性已得到充分证实，但预防策略尚未得到充分探索。良好的个人卫生、洗手和避免吸烟可能会减少呼吸道病毒感染。食用健康均衡的饮食、活性益生菌补充剂和细菌衍生产品，如 OM-85，可能会减少易感儿童的反复感染。目前尚无适合广泛使用的实用抗病毒疗法。
总结
手部卫生是预防普通感冒的最佳措施。健康均衡的饮食、活性益生菌补充剂和免疫刺激物 OM-85 可能会减少哮喘儿童的反复感染。
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