Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands.
J Clin Epidemiol. 2012 Dec;65(12):1337-47. doi: 10.1016/j.jclinepi.2012.06.013. Epub 2012 Sep 10.
The present study evaluates the interpretability of individual changes and assesses the minimal important change (MIC) for improvement and the smallest detectable change (SDC) of the Nurses Work Functioning Questionnaire (NWFQ).
Data of two time points, baseline and 3-month follow-up, of a randomized controlled trial were used. A total of 358 nurses and allied health professionals of one Dutch academic medical center participated at both measurement points. Separate MIC values were calculated for the total score of the NWFQ and its six subscales, using two anchor-based methods: mean change and receiver operating characteristics (ROC) curve methods. Two methods for baseline corrections were applied: subgroup analyses and MIC calculation based on relative change scores. The SDCs were calculated using the standard error of the measurement.
MIC values ranged from 3.4 to 8.3 for the mean change method and from 1.5 to 9.5 for the ROC curve method. In a subgroup with high-baseline scores, the MIC values of the two methods ranged from 4.4 to 29 and 9.5 to 41.5, respectively. The SDC values ranged from 7.2 to 17. Only one MIC value exceeded the SDC; however, 10 of the 14 MIC values exceeded the SDC in the high-baseline group.
Three of the seven NWFQ scales exhibited sufficient interpretability of individual change. For four scales, conclusions on the interpretability of change cannot yet be drawn. SDCs were small compared with the scale range.
本研究评估了个体变化的可解释性,并评估了护士工作功能问卷(NWFQ)的改善最小重要变化(MIC)和最小可检测变化(SDC)。
使用一项随机对照试验的两个时间点(基线和 3 个月随访)的数据。共有来自荷兰一家学术医学中心的 358 名护士和相关卫生专业人员在这两个测量点参与。使用两种基于锚定的方法:平均变化和接收者操作特征(ROC)曲线方法,分别为 NWFQ 总分及其六个分量表计算了 MIC 值。应用了两种基线校正方法:亚组分析和基于相对变化分数的 MIC 计算。使用测量的标准误差计算 SDC。
MIC 值范围为 3.4 到 8.3,用于平均变化方法,范围为 1.5 到 9.5,用于 ROC 曲线方法。在基线分数较高的亚组中,两种方法的 MIC 值范围分别为 4.4 到 29 和 9.5 到 41.5。SDC 值范围为 7.2 到 17。只有一个 MIC 值超过了 SDC;然而,在高基线组中,14 个 MIC 值中有 10 个超过了 SDC。
NWFQ 的七个分量表中有三个显示出个体变化的可解释性。对于四个量表,还不能得出关于变化可解释性的结论。SDC 与量表范围相比很小。