Department of Infectious Diseases and Clinical Microbiology, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.
Braz J Infect Dis. 2012 Sep-Oct;16(5):482-5. doi: 10.1016/j.bjid.2012.08.002. Epub 2012 Sep 11.
Cytomegalovirus (CMV) infection is usually asymptomatic in immunocompetent patients. A mononucleosis-like syndrome may develop in some patients. Various organ involvements (e.g.: encephalitis, meningitis, retinitis, myocarditis, pneumonia, hepatitis, enterocolitis, neuritis), which rarely occur in immunocompetent patients, have also been reported. Cutaneous necrotizing vasculitis caused by CMV infection has been reported very rarely in the literature. Here, a case with a very rare clinical form of CMV infection, presenting with persistent fever and livedo reticularis on the extremities and cutaneous necrotizing vasculitis of the toes, is described, and the relevant literature is reviewed. This case report aims to highlight the possibility of CMV infection to be a cause of cutaneous necrotizing vasculitis.
巨细胞病毒（CMV）感染在免疫功能正常的患者中通常无症状。一些患者可能会出现单核细胞增多症样综合征。也有报道称，各种器官受累（例如脑炎、脑膜炎、视网膜炎、心肌炎、肺炎、肝炎、结肠炎、神经炎）在免疫功能正常的患者中很少发生。文献中也很少报道由 CMV 感染引起的皮肤坏死性血管炎。本文报道了一例极罕见的 CMV 感染临床类型，表现为持续性发热、四肢网状青斑和脚趾皮肤坏死性血管炎，并复习了相关文献。本病例报告旨在强调 CMV 感染可能是皮肤坏死性血管炎的病因之一。
