Department of Community Health, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Prev Med. 2012 Nov;55(5):409-11. doi: 10.1016/j.ypmed.2012.09.002. Epub 2012 Sep 10.
This study aimed to describe the prevalence of metabolic syndrome (MetS) in adolescents of Ho Chi Minh City (HCMC) and to identify components of cardiovascular risk clusters.
A cross-sectional study was conducted on a representative sample of 693 high-school students 13 to 16 years old in 2007. MetS was defined according to five different definitions: the Pediatric International Diabetes Federation, the Adult Treatment Panel III, and the modified definitions by Cook, Weiss, and De Ferranti. Principal components analysis (PCA) was carried out to cluster risk factors.
The prevalence of MetS was high and varied from 3.9% to 12.5%, depending on the criteria used. High levels of triglycerides (or low High Density Lipoprotein Cholesterol) and high blood pressure were the most prevalent components of MetS, while impaired glucose tolerance was the least prevalent. PCA showed three factors in boys (obesity, hypertension, dyslipidemia) that cumulatively explained 64.3%, and four factors in females (obesity, hypertension, dyslipidemia, and hyperglycemia) that accounted for 73.6% of the observed variance of MetS.
The prevalence of MetS in HCMC adolescents was high. Obesity accounts for the maximum variance in clustering and appears to be a more powerful correlate of cardiovascular risk than other variables.
本研究旨在描述胡志明市（HCMC）青少年代谢综合征（MetS）的流行情况，并确定心血管风险聚类的组成部分。
2007 年对 693 名 13 至 16 岁的高中生进行了一项横断面研究。MetS 根据五个不同的定义进行定义：儿科国际糖尿病联合会、成人治疗小组 III 以及 Cook、Weiss 和 De Ferranti 的改良定义。进行主成分分析（PCA）以聚类危险因素。
MetS 的患病率很高，根据使用的标准，从 3.9%到 12.5%不等。高水平的甘油三酯（或低高密度脂蛋白胆固醇）和高血压是 MetS 最常见的组成部分，而葡萄糖耐量受损则是最不常见的。PCA 显示男孩有三个因素（肥胖、高血压、血脂异常），累计解释了 64.3%，女孩有四个因素（肥胖、高血压、血脂异常和高血糖），占 MetS 观察到的变异的 73.6%。
胡志明市青少年代谢综合征的患病率很高。肥胖占聚类最大方差，似乎比其他变量更能预测心血管风险。
