Binh Tran Quang, Phuong Pham Tran, Nhung Bui Thi, Tung Do Dinh
National Institute of Hygiene and Epidemiology, 1 Yersin, Hanoi, Vietnam.
BMC Endocr Disord. 2014 Sep 26;14:77. doi: 10.1186/1472-6823-14-77.
Metabolic syndrome (MetS) is a clustering of metabolic risk factors for cardiovascular diseases and type 2 diabetes. The study aimed to estimate the prevalence of MetS, its components, and their associations among rural middle-aged population in Vietnam.
A cross-sectional study with a representative sample (n = 2443) was conducted to collect data on demographic, socioeconomic, anthropometric, lifestyles, plasma glucose, and lipid profile. The age- and sex-adjusted prevalences of MetS and its components were calculated using the direct standardization. Associations of risk factors with MetS were evaluated using logistic regression, taken into account the confounding factors.
The total age- and sex-adjusted prevalence (95% CI) of MetS was 16.3% (14.0 - 18.6). The most frequent component of MetS was high triglycerides (43.2%), followed by low HDL-C (42.0%), elevated blood pressure (29.2%), high plasma glucose (14.3%), and central obesity (12.3%). Of the total population, only 17.6% did not have any component of MetS and more than 40% had at least two MetS components. The association of MetS with residence, age, body mass index, marital status, and siesta time per day was statistically significant in univariate analysis and replicated in multivariate analysis.
The MetS prevalence and its components are common and major public health burden in the middle-aged adults in Vietnam. Habitants living in urban, being never-married, having an increase in age, BMI, and siesta time per day are significantly associated with MetS, and they should be paid much more attention for screening and implementing preventive activities.
代谢综合征（MetS）是心血管疾病和2型糖尿病的代谢危险因素聚集。本研究旨在估计越南农村中年人群中代谢综合征及其组成成分的患病率及其关联。
进行了一项横断面研究，样本具有代表性（n = 2443），以收集有关人口统计学、社会经济状况、人体测量学、生活方式、血浆葡萄糖和血脂谱的数据。采用直接标准化方法计算代谢综合征及其组成成分的年龄和性别调整患病率。使用逻辑回归评估危险因素与代谢综合征的关联，并考虑混杂因素。
代谢综合征的年龄和性别调整后总患病率（95%CI）为16.3%（14.0 - 18.6）。代谢综合征最常见的组成成分是高甘油三酯（43.2%），其次是低高密度脂蛋白胆固醇（42.0%）、血压升高（29.2%）、高血浆葡萄糖（14.3%）和中心性肥胖（12.3%）。在总人口中，只有17.6%没有代谢综合征的任何组成成分，超过40%至少有两种代谢综合征组成成分。在单因素分析中，代谢综合征与居住地点、年龄、体重指数、婚姻状况和每天午睡时间的关联具有统计学意义，并在多因素分析中得到重复。
代谢综合征的患病率及其组成成分在越南中年成年人中很常见，是主要的公共卫生负担。居住在城市、未婚、年龄增加、体重指数增加和每天午睡时间增加的居民与代谢综合征显著相关，应更加重视对他们进行筛查和开展预防活动。
