Division of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Helsinki, Finland.
Drug Test Anal. 2013 Mar;5(3):186-90. doi: 10.1002/dta.1412. Epub 2012 Sep 13.
Fast analysis of cannabis samples without prior sample preparation or chromatography was performed using desorption atmospheric pressure photoionization-mass spectrometry (DAPPI-MS). The MS(2) spectra of the molecular ions of tetrahydrocannabinol (THC) and cannabidiol (CBD) formed in DAPPI-MS showed distinct product ions, unlike the protonated molecules formed with other ambient mass spectrometry techniques, making possible the reliable identification of THC from cannabis samples.
采用解吸常压光电离-质谱联用技术(DAPPI-MS),无需样品预处理或色谱分离,即可快速分析大麻样品。在 DAPPI-MS 中形成的四氢大麻酚(THC)和大麻二酚(CBD)分子离子的 MS(2)谱显示出独特的产物离子,与其他大气质谱技术形成的质子化分子不同,这使得从大麻样品中可靠地鉴定 THC 成为可能。