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Comparison of four different treatment regimens on coagulation parameters, hormonal and metabolic changes in women with polycystic ovary syndrome.比较四种不同治疗方案对多囊卵巢综合征患者凝血参数、激素和代谢变化的影响。
Arch Gynecol Obstet. 2010 Jan;281(1):35-42. doi: 10.1007/s00404-009-1051-y. Epub 2009 Mar 28.
2
High mean platelet volume, low-grade systemic coagulation and fibrinolytic activation are associated with androgen and insulin levels in polycystic ovary syndrome.多囊卵巢综合征患者的平均血小板体积升高、低度全身凝血和纤溶激活与雄激素及胰岛素水平相关。
Arch Gynecol Obstet. 2009 Aug;280(2):187-93. doi: 10.1007/s00404-008-0884-0. Epub 2008 Dec 24.
3
Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects.多囊卵巢综合征与肥胖和非肥胖受试者的严重血小板及内皮功能障碍相关。
Atherosclerosis. 2009 Jun;204(2):509-14. doi: 10.1016/j.atherosclerosis.2008.09.010. Epub 2008 Sep 17.
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Polycystic ovary syndrome.多囊卵巢综合征
Best Pract Res Clin Obstet Gynaecol. 2008 Apr;22(2):261-74. doi: 10.1016/j.bpobgyn.2007.07.009. Epub 2007 Sep 5.
5
Mean platelet volume in patients with polycystic ovary disease.多囊卵巢疾病患者的平均血小板体积
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Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome.已诊断多囊卵巢综合征的流行病学及不良心血管风险概况
J Clin Endocrinol Metab. 2006 Apr;91(4):1357-63. doi: 10.1210/jc.2005-2430. Epub 2006 Jan 24.
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Abnormalities of coagulation, platelet function, and fibrinolysis associated with syndromes of insulin resistance.与胰岛素抵抗综合征相关的凝血、血小板功能及纤维蛋白溶解异常。
Coron Artery Dis. 2005 Dec;16(8):473-6. doi: 10.1097/00019501-200512000-00003.
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J Clin Endocrinol Metab. 2005 Apr;90(4):1929-35. doi: 10.1210/jc.2004-1045. Epub 2004 Dec 28.
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J Clin Endocrinol Metab. 2004 Nov;89(11):5454-61. doi: 10.1210/jc.2003-032237.
10
Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?急性缺血性脑血管事件患者的平均血小板体积升高是否与更差的预后相关？
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多囊卵巢综合征患者卵巢体积与平均血小板体积及血脂谱的关系。

Relationship of ovarian volume with mean platelet volume and lipid profile in patients with polycystic ovary syndrome.

作者信息

Köşüş Nermin, Köşüş Aydin, Turhan Nilgün Ö

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Fatih University, Ankara, Turkey.

出版信息

Exp Ther Med. 2011 Nov;2(6):1141-1144. doi: 10.3892/etm.2011.327. Epub 2011 Aug 4.

DOI:10.3892/etm.2011.327
PMID:22977634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3440831/
Abstract

The aim of the present study was to evaluate the relationship between ovarian volume (OV) and mean platelet volume (MPV) in women with polycystic ovary syndrome (PCOS). Hormonal parameters and lipid profile of cases, and their relationship to OV were also assessed. Bilateral OV of 210 newly diagnosed PCOS patients and 100 healthy non-hirsute women were measured by ultrasonography. Blood samples were obtained for full blood count, hormone levels and for lipid profiles. It was found that MPV increased gradually as OV increased. This implies a higher risk of hypercoagulability and therefore an increased risk of future cardiovascular disease.

摘要

本研究的目的是评估多囊卵巢综合征（PCOS）女性的卵巢体积（OV）与平均血小板体积（MPV）之间的关系。还评估了病例的激素参数和血脂谱及其与OV的关系。通过超声检查测量了210例新诊断的PCOS患者和100例健康非多毛女性的双侧卵巢体积。采集血样进行全血细胞计数、激素水平和血脂谱检测。结果发现，随着OV的增加，MPV逐渐升高。这意味着高凝风险更高，因此未来患心血管疾病的风险增加。