评价瘦多囊卵巢综合征女性的平均血小板体积值。
Evaluation of Mean Platelet Volume values in lean women with polycystic ovary syndrome.
机构信息
Dilek Benk Silfeler, Department of Obstetrics and Gynecology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
Raziye Keskin Kurt, Department of Obstetrics and Gynecology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
出版信息
Pak J Med Sci. 2014 May;30(3):589-92. doi: 10.12669/pjms.303.4475.
OBJECTIVE
Mean Platelet Volume (MPV) is an important indicator of platelet activation. It is known that MPV increases in patients with coronory artery disease, diabetes mellitus, atherosclerosis and Polycystic ovary syndrome (PCOS). Our aim was to measure the MPV in lean patients with polycystic ovary syndrome.
METHODS
The present study was designed to examine the platelet function by measuring MPV in non-obese women with PCOS. A total of 50 outpatients with PCOS were included. The control group consisted of 50 healthy subjects. Serum platelet, MPV, and white blood cell (WBC) levels were compared and evaluated retrospectively in all participants. These values were compared by statistical analysis.
RESULTS
There were no statistically significant difference in between groups regarding MPV (p═0.357), WBC (p═0,414) and platelet (p═0,666).
CONCLUSION
There are studies implying MPV increase in PCOS patients, in our patients MPV levels did not correlate with PCOS except for patients with obesity. We think that PCOS itself has no effect on MPV levels and obesity changes MPV levels.
目的
平均血小板体积（MPV）是血小板活化的一个重要指标。已知冠心病、糖尿病、动脉粥样硬化和多囊卵巢综合征（PCOS）患者的 MPV 会增加。我们的目的是测量瘦型多囊卵巢综合征患者的 MPV。
方法
本研究旨在通过测量非肥胖多囊卵巢综合征患者的 MPV 来检查血小板功能。共纳入 50 例多囊卵巢综合征门诊患者。对照组由 50 名健康受试者组成。对所有参与者的血小板、MPV 和白细胞（WBC）水平进行回顾性比较和评估。通过统计学分析比较这些值。
结果
MPV（p=0.357）、WBC（p=0.414）和血小板（p=0.666）在两组之间无统计学差异。
结论
有研究表明多囊卵巢综合征患者的 MPV 增加，但在我们的患者中，MPV 水平与多囊卵巢综合征无关，除了肥胖患者。我们认为多囊卵巢综合征本身对 MPV 水平没有影响，肥胖会改变 MPV 水平。
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