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本文引用的文献

1
Relationship of ovarian volume with mean platelet volume and lipid profile in patients with polycystic ovary syndrome.多囊卵巢综合征患者卵巢体积与平均血小板体积及血脂谱的关系。
Exp Ther Med. 2011 Nov;2(6):1141-1144. doi: 10.3892/etm.2011.327. Epub 2011 Aug 4.
2
Polycystic ovary syndrome: focus on platelets and prothrombotic risk.多囊卵巢综合征：聚焦于血小板与血栓形成前风险。
South Med J. 2011 Mar;104(3):174-8. doi: 10.1097/SMJ.0b013e31820c0172.
3
Polycystic ovarian syndrome and the risk of cardiovascular disease and thrombosis.多囊卵巢综合征与心血管疾病和血栓形成的风险。
Semin Thromb Hemost. 2009 Oct;35(7):613-20. doi: 10.1055/s-0029-1242715.
4
Comparison of four different treatment regimens on coagulation parameters, hormonal and metabolic changes in women with polycystic ovary syndrome.比较四种不同治疗方案对多囊卵巢综合征患者凝血参数、激素和代谢变化的影响。
Arch Gynecol Obstet. 2010 Jan;281(1):35-42. doi: 10.1007/s00404-009-1051-y. Epub 2009 Mar 28.
5
High mean platelet volume, low-grade systemic coagulation and fibrinolytic activation are associated with androgen and insulin levels in polycystic ovary syndrome.多囊卵巢综合征患者的平均血小板体积升高、低度全身凝血和纤溶激活与雄激素及胰岛素水平相关。
Arch Gynecol Obstet. 2009 Aug;280(2):187-93. doi: 10.1007/s00404-008-0884-0. Epub 2008 Dec 24.
6
Platelet activation in patients with Familial Mediterranean Fever.家族性地中海热患者的血小板活化
Platelets. 2008 Sep;19(6):405-8. doi: 10.1080/09537100802187121.
7
Polycystic ovary syndrome.多囊卵巢综合征
Best Pract Res Clin Obstet Gynaecol. 2008 Apr;22(2):261-74. doi: 10.1016/j.bpobgyn.2007.07.009. Epub 2007 Sep 5.
8
Comparison of fibrinolytic and metabolic system parameters in obese patients with polycystic ovary syndrome and women with simple obesity.多囊卵巢综合征肥胖患者与单纯肥胖女性纤溶和代谢系统参数的比较。
Gynecol Endocrinol. 2006 Nov;22(11):651-4. doi: 10.1080/09513590601005805.
9
Abnormalities of coagulation, platelet function, and fibrinolysis associated with syndromes of insulin resistance.与胰岛素抵抗综合征相关的凝血、血小板功能及纤维蛋白溶解异常。
Coron Artery Dis. 2005 Dec;16(8):473-6. doi: 10.1097/00019501-200512000-00003.
10
Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study.白细胞计数作为绝经后女性心血管事件和死亡率的预测指标：妇女健康倡议观察性研究
Arch Intern Med. 2005 Mar 14;165(5):500-8. doi: 10.1001/archinte.165.5.500.

评价瘦多囊卵巢综合征女性的平均血小板体积值。

Evaluation of Mean Platelet Volume values in lean women with polycystic ovary syndrome.

机构信息

Dilek Benk Silfeler, Department of Obstetrics and Gynecology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.

Raziye Keskin Kurt, Department of Obstetrics and Gynecology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.

出版信息

Pak J Med Sci. 2014 May;30(3):589-92. doi: 10.12669/pjms.303.4475.

DOI:10.12669/pjms.303.4475
PMID:24948985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4048512/
Abstract

OBJECTIVE

Mean Platelet Volume (MPV) is an important indicator of platelet activation. It is known that MPV increases in patients with coronory artery disease, diabetes mellitus, atherosclerosis and Polycystic ovary syndrome (PCOS). Our aim was to measure the MPV in lean patients with polycystic ovary syndrome.

METHODS

The present study was designed to examine the platelet function by measuring MPV in non-obese women with PCOS. A total of 50 outpatients with PCOS were included. The control group consisted of 50 healthy subjects. Serum platelet, MPV, and white blood cell (WBC) levels were compared and evaluated retrospectively in all participants. These values were compared by statistical analysis.

RESULTS

There were no statistically significant difference in between groups regarding MPV (p═0.357), WBC (p═0,414) and platelet (p═0,666).

CONCLUSION

There are studies implying MPV increase in PCOS patients, in our patients MPV levels did not correlate with PCOS except for patients with obesity. We think that PCOS itself has no effect on MPV levels and obesity changes MPV levels.

摘要

目的

平均血小板体积（MPV）是血小板活化的一个重要指标。已知冠心病、糖尿病、动脉粥样硬化和多囊卵巢综合征（PCOS）患者的 MPV 会增加。我们的目的是测量瘦型多囊卵巢综合征患者的 MPV。

方法

本研究旨在通过测量非肥胖多囊卵巢综合征患者的 MPV 来检查血小板功能。共纳入 50 例多囊卵巢综合征门诊患者。对照组由 50 名健康受试者组成。对所有参与者的血小板、MPV 和白细胞（WBC）水平进行回顾性比较和评估。通过统计学分析比较这些值。

结果

MPV（p=0.357）、WBC（p=0.414）和血小板（p=0.666）在两组之间无统计学差异。

结论

有研究表明多囊卵巢综合征患者的 MPV 增加，但在我们的患者中，MPV 水平与多囊卵巢综合征无关，除了肥胖患者。我们认为多囊卵巢综合征本身对 MPV 水平没有影响，肥胖会改变 MPV 水平。