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印度海草的化学成分和对尿路感染病原体的抗菌活性。

Chemical composition and antibacterial activity of Indian seagrasses against urinary tract pathogens.

机构信息

Centre of Advanced Study in Marine Biology, Faculty of Marine Science, Annamalai University, Parangipettai 608 502, Tamil Nadu, India.

出版信息

Food Chem. 2012 Dec 15;135(4):2470-3. doi: 10.1016/j.foodchem.2012.07.070. Epub 2012 Jul 20.

Abstract

Seagrasses have a long history of being used for a variety of remedial purposes, such as the fever, skin diseases, muscle pains, wounds and stomach problems. Hence it is essential to study their bioactive metabolites and medicinal properties when considering their food applications. The chemical composition of six seagrasses were determined and evaluated for their potential to urinary tract infection bacteria (UTI). The chemical composition determined by GC-MS yielded 24 compounds. For the first time 4H-Pyran-4-one-2,3-dihydro-3,5-dihydroxy-6-methyl- (6.68%), d-allose (3.67%) and 5-Caranol, trans,trans-(+)- (2.14%) were identified from Halodule pinifolia. d-Allose is a aldo-hexose (sugar) used as a potential inhibitor of glycosidases and low-calorie carbohydrate sweeteners. Among the six seagrasses tested, H. pinifolia and Cymodocea rotundata exhibited predominant growth inhibitory activity against all the UTI bacteria. This study shows the presence of various biological metabolites in tested seagrasses that can be used effectively in food and pharmacological industries.

摘要

海草在治疗发热、皮肤病、肌肉疼痛、伤口和胃病等方面有着悠久的历史。因此,在考虑其食用应用时,研究其生物活性代谢物和药用特性至关重要。本研究测定了六种海草的化学成分,并评估了它们对尿路感染细菌(UTI)的潜在作用。GC-MS 测定的化学成分产生了 24 种化合物。这是首次从 Halodule pinifolia 中鉴定出 4H-Pyran-4-one-2,3-dihydro-3,5-dihydroxy-6-methyl-(6.68%)、d-Allose(3.67%)和 5-Caranol,trans,trans-(+)-(2.14%)。d-Allose 是一种 aldopentose(糖),可用作糖苷酶的潜在抑制剂和低热量碳水化合物甜味剂。在测试的六种海草中,H. pinifolia 和 Cymodocea rotundata 对所有 UTI 细菌表现出明显的生长抑制活性。本研究表明,测试的海草中存在各种生物代谢物,可有效用于食品和药理学行业。

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