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[Reciprocal differences in the susceptibility to induction by ortho-aminoazotoluene of liver and vascular tumors in A/HeJ and CC67BR/Mv mice].

作者信息

Kaledin V I, Semenova L A

出版信息

Eksp Onkol. 1990;12(1):16-8.

PMID:2298137
Abstract

When administered subcutaneously, ortho-aminoazotoluene induces predominantly liver tumours in A/HeJ mice but vascular tumours (located mainly in the interscapular brown fat pads) in CC57BR/Mv mice. Liver tumours are more frequent in females, while vascular tumours--in males. Under crossing, the susceptibility to induction of the both types of tumours in male F1 hybrids is inherited intermediately, whereas in females the resistance to induction of vascular tumours predominates.

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