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[Different predisposition to the development of spontaneous and induced liver tumors in mice of different strains and their hybrids].

作者信息

Kaledin V I, Serova I A, Semenova L A

出版信息

Eksp Onkol. 1990;12(4):28-30.

PMID:2379484
Abstract

No correlation between the sensitivity to induction of liver tumours by ortho-aminoazotoluene and predisposition to spontaneous development of these tumours was found in mice. Under crossing the predisposition to spontaneous tumours was inherited dominantly, while sensitivity to their induction was inherited by the intermediate type. Spontaneous hepatomas were more frequent in males, whereas induced onesin females of the same genotype.

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