Petrov S A
Eksp Onkol. 1990;12(1):31-4.
The results of the study of primary morphological manifestation of neuroleukemia (MMN) by mice with transplanting leukemia strains L 1210, P-388, L 5178Y, and are presented. It is determined that the MMN development degree depends on the leukemia cells dissemination amplitude after their transplantation and, in particular, on the degree of the bone-marrow affection, from which the leukemia cells grow into the dura mater encephali and epidural fat of the vertebral canal from the side of skull bones and vertebral canal. The analogous dependence is assumed to be present in a man and, therefore, there appears the possibility of using it for the neuroleukemia development frequency prognosing.
介绍了通过移植白血病菌株L 1210、P - 388、L 5178Y的小鼠对神经白血病（MMN）主要形态学表现的研究结果。已确定MMN的发展程度取决于白血病细胞移植后的扩散幅度，尤其取决于骨髓受影响的程度，白血病细胞从颅骨和椎管一侧生长到硬脑膜和椎管的硬膜外脂肪中。假定在人类中也存在类似的依赖性，因此，有可能将其用于预测神经白血病的发生频率。
