Petrov S A
Gematol Transfuziol. 1992 May-Jun;37(5-6):23-5.
The whole skull and spinal column were histologically studied in 55 suckling mice (intact and with transplantable leukemia). It was stated that the lesion of the vertebral canal prevailed due to the extensive growth of leukemic infiltrates in the bodies of the vertebra which had incompletely formed cortical plate of the bone tissue. Such age-dependent unfinished formation of the bone marrow tissue may predispose a rapid development of neuroleukemia.
对55只乳鼠(完整的和患有可移植性白血病的)的整个颅骨和脊柱进行了组织学研究。结果表明,由于白血病浸润在椎体中广泛生长,而椎体的骨组织皮质板尚未完全形成,椎管病变较为普遍。骨髓组织这种与年龄相关的未完成形成可能易导致神经白血病的快速发展。