Institute of Entomology and Molecular Biology, College of Life Sciences, Chongqing Normal University, Chongqing 401331, China.
Infect Genet Evol. 2012 Dec;12(8):1958-67. doi: 10.1016/j.meegid.2012.08.007. Epub 2012 Sep 12.
Anopheles aconitus is a well-known vector of malaria and is broadly distributed in the Oriental Region, yet there is no information on its population genetic characteristics. In this study, the genetic differentiation among populations was examined using 140 mtDNA COII sequences from 21 sites throughout Southern China, Myanmar, Vietnam, Thailand, Laos and Sri Lanka. The population in Sri Lanka has characteristic rDNA D3 and ITS2, mtDNA COII and ND5 haplotypes, and may be considered a distinct subspecies. Clear genetic structure was observed with highly significant genetic variation present among population groups in Southeast Asia. The greatest genetic diversity exists in Yunnan and Myanmar population groups. All population groups are significantly different from one another in pairwise Fst values, except Northern Thailand with Central Thailand. Mismatch distributions and extremely significant F(s) values suggest that the populations passed through a recent demographic expansion. These patterns are discussed in relation to the likely biogeographic history of the region and compared to other Anopheles species.
中华按蚊是一种广布于东洋界的疟疾媒介蚊种，然而有关其种群遗传特征的信息却很少。本研究利用来自中国南方、缅甸、越南、泰国、老挝和斯里兰卡 21 个地点的 140 个 mtDNA COII 序列，检测了种群间的遗传分化。斯里兰卡种群具有独特的 rDNA D3 和 ITS2、mtDNA COII 和 ND5 单倍型，可能被视为一个独特的亚种。东南亚的种群具有明显的遗传结构，种群间存在高度显著的遗传变异。云南和缅甸种群的遗传多样性最大。除了泰国北部与中部之外，所有种群组间在成对 Fst 值上均存在显著差异。歧点分布和极度显著的 F(s)值表明，这些种群经历了近期的种群扩张。这些模式与该地区可能的生物地理历史有关，并与其他按蚊物种进行了比较。
