Erekson Elisabeth A, Yip Sallis O, Martin Deanna K, Ciarleglio Maria M, Connell Kathleen A, Fried Terri R
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06519, USA.
Female Pelvic Med Reconstr Surg. 2012 Sep-Oct;18(5):274-80. doi: 10.1097/SPV.0b013e318263a210.
The objective of this study was to create a clinical prediction tool to differentiate women at risk for postoperative complications after benign gynecologic surgery.
We utilized the 2005 to 2009 American College of Surgeons National Surgical Quality Improvement Program participant use data files to perform a secondary data-set analysis of women older than 16 years who underwent benign gynecologic procedures. We then temporally divided women into 2 similar cohorts. Our derivation cohort included all women undergoing benign gynecologic procedures in 2005 to 2008. Our validation cohort included all women undergoing benign gynecologic procedures in 2009. The primary outcome, composite 30-day major postoperative complications, was analyzed as a dichotomous variable. A prediction tool was then constructed to predict the occurrence of postoperative complications built from the logistic regression model by rounding the value of each estimated β coefficient to the nearest integer. An individual's risk score was then computed by summing the number of points based on her preoperative characteristics. This risk score was then used to categorize women into low-, medium-, and high-risk groups.
A prediction tool for benign gynecologic procedures identified women at low (2.7% and 2.4%), medium (6.3% and 6.8%), and high (29.5% and 23.8%) risk of complications in the derivation and validation cohorts, respectively.
A prediction tool can differentiate women at risk for postoperative complications after benign gynecologic surgery.
本研究的目的是创建一种临床预测工具,以区分良性妇科手术后有术后并发症风险的女性。
我们利用2005年至2009年美国外科医师学会国家外科质量改进计划参与者使用的数据文件,对16岁以上接受良性妇科手术的女性进行二次数据集分析。然后,我们将女性按时间分为两个相似的队列。我们的推导队列包括2005年至2008年接受良性妇科手术的所有女性。我们的验证队列包括2009年接受良性妇科手术的所有女性。主要结局,即30天术后主要并发症的复合情况,被分析为一个二分变量。然后构建一个预测工具,通过将每个估计的β系数值四舍五入到最接近的整数,从逻辑回归模型中预测术后并发症的发生情况。然后根据个体的术前特征计算其风险评分。然后使用该风险评分将女性分为低、中、高风险组。
良性妇科手术的预测工具在推导队列和验证队列中分别识别出并发症风险低(2.7%和2.4%)、中(6.3%和6.8%)、高(29.5%和23.8%)的女性。
一种预测工具可以区分良性妇科手术后有术后并发症风险的女性。